| Literature DB >> 28428997 |
Dongyao Wang1, Yan Cao, Leyi Zheng, Diya Lv, Langdong Chen, Xinrui Xing, Zhenyu Zhu, Xiaoyu Li, Yifeng Chai.
Abstract
Matrine is a plant alkaloid and a major active component in the Chinese medical herb Sophora flavescens. Matrine has shown potent anti-cancer activities but its molecular target(s) and mechanism are still unknown. Using the photo-affinity labeling approach, for the first time, Annexin A2 was identified as a direct-binding target of matrine in cancer cells.Entities:
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Year: 2017 PMID： 28428997 DOI： 10.1039/c7cc02227a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222