Literature DB >> 2842766

Molecular cloning and sequencing of DNA complementary to chicken liver fatty acid synthase mRNA.

Z Y Yuan1, W Liu, G G Hammes.   

Abstract

The cDNA corresponding to 4.18 kilobases (kb) of the mRNA of chicken liver fatty acid synthase has been cloned and sequenced. The cDNA corresponds to the 3' end of the mRNA and consists of a 1.87-kb noncoding tail and a 2.31-kb region encoding 769 amino acids of the C terminus of the enzyme. The thioesterase at the C terminus, preceded by the acyl carrier protein, can be identified from known amino acid sequences. However, the identity of the enzymes N terminal to the acyl carrier protein could not be ascertained. The partial amino acid sequence of the chicken liver fatty acid synthase shows greater than 70% similarity with the rat mammary gland enzyme.

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Year:  1988        PMID： 2842766      PMCID： PMC281963          DOI： 10.1073/pnas.85.17.6328

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  11 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

Review 2.  Transcription termination and 3' processing: the end is in site!

Authors:  M L Birnstiel; M Busslinger; K Strub
Journal:  Cell       Date:  1985-06       Impact factor: 41.582

3.  Molecular cloning and sequencing of a cDNA encoding the acyl carrier protein and its flanking domains in the mammalian fatty acid synthetase.

Authors:  A Witkowski; J Naggert; J Mikkelsen; S Smith
Journal:  Eur J Biochem       Date:  1987-06-15

4.  The fatty acid synthase gene in avian liver. Two mRNAs are expressed and regulated in parallel by feeding, primarily at the level of transcription.

Authors:  D W Back; M J Goldman; J E Fisch; R S Ochs; A G Goodridge
Journal:  J Biol Chem       Date:  1986-03-25       Impact factor: 5.157

Review 5.  Fatty acid synthesis and its regulation.

Authors:  S J Wakil; J K Stoops; V C Joshi
Journal:  Annu Rev Biochem       Date:  1983       Impact factor: 23.643

6.  Molecular cloning and sequencing of a cDNA encoding the thioesterase domain of the rat fatty acid synthetase.

Authors:  J Naggert; A Witkowski; J Mikkelsen; S Smith
Journal:  J Biol Chem       Date:  1988-01-25       Impact factor: 5.157

7.  The architecture of the animal fatty acid synthetase complex. IV. Mapping of active centers and model for the mechanism of action.

Authors:  Y Tsukamoto; H Wong; J S Mattick; S J Wakil
Journal:  J Biol Chem       Date:  1983-12-25       Impact factor: 5.157

8.  The architecture of the animal fatty acid synthetase. I. Proteolytic dissection and peptide mapping.

Authors:  J S Mattick; Y Tsukamoto; J Nickless; S J Wakil
Journal:  J Biol Chem       Date:  1983-12-25       Impact factor: 5.157

9.  Fatty acid synthase: elementary steps in catalysis and regulation.

Authors:  G G Hammes
Journal:  Curr Top Cell Regul       Date:  1985

10.  Fluorescence studies of chicken liver fatty acid synthase. Segmental flexibility and distance measurements.

Authors:  Z Y Yuan; G G Hammes
Journal:  J Biol Chem       Date:  1986-10-15       Impact factor: 5.157
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  17 in total

1.  Quaternary structure of human fatty acid synthase by electron cryomicroscopy.

Authors:  Jacob Brink; Steven J Ludtke; Chao-Yuh Yang; Zei-Wei Gu; Salih J Wakil; Wah Chiu
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-26       Impact factor: 11.205

2.  The pentafunctional FAS1 genes of Saccharomyces cerevisiae and Yarrowia lipolytica are co-linear and considerably longer than previously estimated.

Authors:  H Köttig; G Rottner; K F Beck; M Schweizer; E Schweizer
Journal:  Mol Gen Genet       Date:  1991-04

3.  Amino acid activation and polymerization at modular multienzymes in nonribosomal peptide biosynthesis.

Authors:  T Stein; J Vater
Journal:  Amino Acids       Date:  1996-09       Impact factor: 3.520

4.  Human fatty acid synthase: role of interdomain in the formation of catalytically active synthase dimer.

Authors:  S S Chirala; A Jayakumar; Z W Gu; S J Wakil
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

5.  Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase.

Authors:  C M Amy; A Witkowski; J Naggert; B Williams; Z Randhawa; S Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

6.  Molecular cloning and sequencing of chicken liver fatty acid synthase cDNA.

Authors:  K P Holzer; W Liu; G G Hammes
Journal:  Proc Natl Acad Sci U S A       Date:  1989-06       Impact factor: 11.205

7.  Identification of domains in an Arabidopsis acyl carrier protein gene promoter required for maximal organ-specific expression.

Authors:  S R Baerson; M G Vander Heiden; G K Lamppa
Journal:  Plant Mol Biol       Date:  1994-12       Impact factor: 4.076

8.  Cloning, characterization, and high-level expression in Escherichia coli of the Saccharopolyspora erythraea gene encoding an acyl carrier protein potentially involved in fatty acid biosynthesis.

Authors:  W P Revill; P F Leadlay
Journal:  J Bacteriol       Date:  1991-07       Impact factor: 3.490

9.  Characterization of the polyketide synthase gene (pksL1) required for aflatoxin biosynthesis in Aspergillus parasiticus.

Authors:  G H Feng; T J Leonard
Journal:  J Bacteriol       Date:  1995-11       Impact factor: 3.490

10.  Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.

Authors:  H Shimano; J D Horton; R E Hammer; I Shimomura; M S Brown; J L Goldstein
Journal:  J Clin Invest       Date:  1996-10-01       Impact factor: 14.808
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