Literature DB >> 28426761

Correction: DHA Supplemented in Peptamen Diet Offers No Advantage in Pathways to Amyloidosis: Is It Time to Evaluate Composite Lipid Diet?

Zareen Amtul, Mary Keet, Lin Wang, Peter Merrifield, David Westaway, Richard F Rozmahel.   

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0024094.].

Entities:  

Year:  2017        PMID: 28426761      PMCID: PMC5398715          DOI: 10.1371/journal.pone.0176644

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


Fig 2 is incorrect. The appearance of certain bands on Western blot images are compromised. The actin bands of Tg/pep in b-secretase pathway section are switched with the actin bands in Tg/pep+DHA bands of Abeta metabolism section. The authors have provided a corrected version here.
Fig 2

Effects of pep+DHA diet on protein levels.

A. Western blots of APP, BACE, APP-CTFs (α/β), IDE, PrP and β-actin protein levels in the frontal cortices of Tg/chow, Tg/pep and Tg/pep+DHA mice. Respective molecular weights (Kd) are shown on the left. Plot shows quantitative analysis of protein levels as mean ± S.E.M., (n = 6 for each experiment, out of 6 only 3 animals each are shown for Tg/chow, Tg/pep and Tg/pep+DHA mice in Western blots), ***p<0.001, **p<0.01 and *p<0.05.

Effects of pep+DHA diet on protein levels.

A. Western blots of APP, BACE, APP-CTFs (α/β), IDE, PrP and β-actin protein levels in the frontal cortices of Tg/chow, Tg/pep and Tg/pep+DHA mice. Respective molecular weights (Kd) are shown on the left. Plot shows quantitative analysis of protein levels as mean ± S.E.M., (n = 6 for each experiment, out of 6 only 3 animals each are shown for Tg/chow, Tg/pep and Tg/pep+DHA mice in Western blots), ***p<0.001, **p<0.01 and *p<0.05.
  1 in total

1.  DHA supplemented in peptamen diet offers no advantage in pathways to amyloidosis: is it time to evaluate composite lipid diet?

Authors:  Zareen Amtul; Mary Keet; Lin Wang; Peter Merrifield; David Westaway; Richard F Rozmahel
Journal:  PLoS One       Date:  2011-09-08       Impact factor: 3.240

  1 in total

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