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Literature DB >> 28426274

A critical appraisal of 'Shingrix', a novel herpes zoster subunit vaccine (HZ/Su or GSK1437173A) for varicella zoster virus.

Tehmina Bharucha¹, Damien Ming², Judith Breuer^1,3.

Abstract

HZ/Su, branded as 'Shingrix', is one of the newest vaccines to be submitted for multi-national regulatory approval. It is targeted to prevent shingles, a global concern with aging populations. A live attenuated vaccine for shingles has been available for over a decade, however it is contraindicated in specific subgroups of people, and there are added concerns regarding long-term immunogenicity. HZ/Su is the first subunit vaccine developed to protect against shingles. This paper provides a critical appraisal of current evidence regarding HZ/Su.

Entities: Species

Keywords: immunisation/vaccination; public health; shingles; varicella/herpes zoster virus

Mesh：

Substances：

Year: 2017 PMID： 28426274 PMCID： PMC5557227 DOI： 10.1080/21645515.2017.1317410

Source DB: PubMed Journal: Hum Vaccin Immunother ISSN： 2164-5515 Impact factor: 3.452

42 in total

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Authors: Nathalie Garçon; Patrick Chomez; Marcelle Van Mechelen
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8. Safety and immunogenicity of an adjuvanted herpes zoster subunit candidate vaccine in HIV-infected adults: a phase 1/2a randomized, placebo-controlled study.

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Journal: J Infect Dis Date: 2014-11-03 Impact factor: 5.226

9. Efficacy and safety of the RTS,S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 African sites.

Authors:
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Authors: Kosuke Kawai; Berhanu G Gebremeskel; Camilo J Acosta
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14 in total

Review 1. Infectious Complications of Biological and Small Molecule Targeted Immunomodulatory Therapies.

Authors: Joshua S Davis; David Ferreira; Emma Paige; Craig Gedye; Michael Boyle
Journal: Clin Microbiol Rev Date: 2020-06-10 Impact factor: 26.132

2. Acute retinal necrosis following recombinant subunit varicella-zoster virus vaccine.

Authors: Rebecca I Chen; Jordan D Deaner; Sunil K Srivastava; Careen Y Lowder
Journal: Am J Ophthalmol Case Rep Date: 2020-10-08

Review 3. Promoting Healthy Ageing in South Africa Through Vaccination of the Elderly.

Authors: Mncengeli Sibanda; Johanna C Meyer; Kesentseng J Mahlaba; Rosemary J Burnett
Journal: Front Public Health Date: 2021-04-26

4. 3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates.

Authors: Sudhir Pai Kasturi; Mohammed Ata Ur Rasheed; Colin Havenar-Daughton; Mathew Pham; Traci Legere; Zarpheen Jinnah Sher; Yevgeny Kovalenkov; Sanjeev Gumber; Jessica Y Huang; Raphael Gottardo; William Fulp; Alicia Sato; Sheetal Sawant; Sherry Stanfield-Oakley; Nicole Yates; Celia LaBranche; S Munir Alam; Georgia Tomaras; Guido Ferrari; David Montefiori; Jens Wrammert; Francois Villinger; Mark Tomai; John Vasilakos; Christopher B Fox; Steven G Reed; Barton F Haynes; Shane Crotty; Rafi Ahmed; Bali Pulendran
Journal: Sci Immunol Date: 2020-06-19

10. Evaluation of Reporting Quality in Randomised Controlled Trials of Acupuncture for Acute Herpes Zoster by the CONSORT Statement and STRICTA Guidelines.

Authors: Guifeng Qian; Jingchun Zeng; Liming Lu; Wenya Pei; Kun Liu; Zhenke Luo; Yalin She; Pande Zhang; Guohua Lin
Journal: Evid Based Complement Alternat Med Date: 2020-02-18 Impact factor: 2.629

A critical appraisal of 'Shingrix', a novel herpes zoster subunit vaccine (HZ/Su or GSK1437173A) for varicella zoster virus.

1. Epidemiology of primary varicella and herpes zoster hospitalizations: the pre-varicella vaccine era.

Review 2. Herpes zoster epidemiology, management, and disease and economic burden in Europe: a multidisciplinary perspective.

Review 3. The perfect mix: recent progress in adjuvant research.

Review 4. Glycoproteins encoded by varicella-zoster virus: biosynthesis, phosphorylation, and intracellular trafficking.

Review 5. Antiviral treatment for preventing postherpetic neuralgia.

Review 6. Vaccines for preventing herpes zoster in older adults.

Review 7. GlaxoSmithKline Adjuvant Systems in vaccines: concepts, achievements and perspectives.

8. Safety and immunogenicity of an adjuvanted herpes zoster subunit candidate vaccine in HIV-infected adults: a phase 1/2a randomized, placebo-controlled study.

9. Efficacy and safety of the RTS,S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 African sites.

Review 10. Systematic review of incidence and complications of herpes zoster: towards a global perspective.

Review 1. Infectious Complications of Biological and Small Molecule Targeted Immunomodulatory Therapies.

2. Acute retinal necrosis following recombinant subunit varicella-zoster virus vaccine.

Review 3. Promoting Healthy Ageing in South Africa Through Vaccination of the Elderly.

4. 3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates.

5. Uveitis Sarcoidosis Presumably Initiated After Administration of Shingrix Vaccine.

Review 6. Uveitis as a Predictor of Predisposition to Autoimmunity.

Review 7. New horizons in adjuvants for vaccine development.

8. Cryo-EM structure of S-Trimer, a subunit vaccine candidate for COVID-19.

Review 9. Recombinant Zoster Vaccine (Shingrix^®): A Review in Herpes Zoster.

10. Evaluation of Reporting Quality in Randomised Controlled Trials of Acupuncture for Acute Herpes Zoster by the CONSORT Statement and STRICTA Guidelines.

Review 2. Herpes zoster epidemiology, management, and disease and economic burden in Europe: a multidisciplinary perspective.

Review 3. The perfect mix: recent progress in adjuvant research.

Review 4. Glycoproteins encoded by varicella-zoster virus: biosynthesis, phosphorylation, and intracellular trafficking.

Review 5. Antiviral treatment for preventing postherpetic neuralgia.

Review 6. Vaccines for preventing herpes zoster in older adults.

Review 7. GlaxoSmithKline Adjuvant Systems in vaccines: concepts, achievements and perspectives.

Review 10. Systematic review of incidence and complications of herpes zoster: towards a global perspective.

Review 1. Infectious Complications of Biological and Small Molecule Targeted Immunomodulatory Therapies.

Review 3. Promoting Healthy Ageing in South Africa Through Vaccination of the Elderly.

Review 6. Uveitis as a Predictor of Predisposition to Autoimmunity.

Review 7. New horizons in adjuvants for vaccine development.

Review 9. Recombinant Zoster Vaccine (Shingrix®): A Review in Herpes Zoster.

Review 9. Recombinant Zoster Vaccine (Shingrix^®): A Review in Herpes Zoster.