Literature DB >> 28426212

Construction of β-Trifluoromethyl Enol Ether via Base-Promoted C-O Coupling and Rearrangement of Hydrogen Atom.

Kun Dai1, Kuan Wang1, Yang Li2, Jian-Gang Chen1, Zhong-Wen Liu1, Jian Lu2, Zhao-Tie Liu1.   

Abstract

A novel, high-efficiency and high-selectivity construction of β-trifluoromethyl enol ether via base-induced/promoted C-O coupling of trifluoromethylated vinyl chloride and phenols is presented with a broad substrate scope. The reaction mechanism, especially the significantly high selectivity, was excavated and understood via DFT calculation and is well supported by the experimental observation.

Entities:  

Year:  2017        PMID： 28426212     DOI： 10.1021/acs.joc.7b00396

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Metal-free catalytic hydrocarboxylation of hexafluorobut-2-yne.

Authors:  Ji-Jun Zeng; Bo Zhao; Xiao-Bo Tang; Sheng Han; Zhi-Qiang Yang; Ze-Peng Liu; Wei Zhang; Jian Lu
Journal:  RSC Adv       Date:  2021-12-06       Impact factor: 4.036

2.  Synthesis of aryl 2-bromo-2-chloro-1,1-difluoroethyl ethers through the base-mediated reaction between phenols and halothane.

Authors:  Yukiko Karuo; Ayaka Kametani; Atsushi Tarui; Kazuyuki Sato; Kentaro Kawai; Masaaki Omote
Journal:  Beilstein J Org Chem       Date:  2021-01-11       Impact factor: 2.883

3.  Insight into the Intermolecular Interaction and Free Radical Polymerizability of Methacrylates in Supercritical Carbon Dioxide.

Authors:  Rui-Qing Li; Ming-Xi Wang; Qi-Yu Zhang; Jian-Gang Chen; Kuan Wang; Xiao-Yong Zhang; Shukun Shen; Zhao-Tie Liu; Zhong-Wen Liu; Jinqiang Jiang
Journal:  Polymers (Basel)       Date:  2020-01-02       Impact factor: 4.329
  3 in total

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