| Literature DB >> 28425520 |
S Petralia1, E L Sciuto2, M L Di Pietro3, M Zimbone2, M G Grimaldi2, S Conoci1.
Abstract
An innovative chemical strategy integrated in a miniaturized electrochemical device was developed for sensitive detection of a pathogen genome (HBV virus) without any amplification step. The results show a limit of detection comparable to the standard qRT-PCR method (20 copies per reaction), paving the way to future development of genetic PoC devices addressing automatized and low-cost molecular diagnostics.Mesh：
Year: 2017 PMID： 28425520 DOI： 10.1039/c7an00202e
Source DB: PubMed Journal: Analyst ISSN： 0003-2654 Impact factor: 4.616