Literature DB >> 2842522

The efficacy of high-dose 4'epidoxorubicin in hepatocellular carcinoma.

W Shiu1, N Leung, M Li, W T Leung, A K Li.   

Abstract

An open phase II study of high-dose 4'epidoxorubicin (90 mg/m2) was conducted in 33 patients with inoperable hepatocellular carcinoma. Three out of the 33 (9%) patients showed tumour response. The treatment was relatively well tolerated with a moderate degree of haematological toxicity and alopecia, and a mild degree of nausea and vomiting. The overall median survival was 72 days with a prolongation in the patients who showed some response.

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Year:  1988        PMID: 2842522

Source DB:  PubMed          Journal:  Jpn J Clin Oncol        ISSN: 0368-2811            Impact factor:   3.019


  3 in total

1.  Phase II study of high-dose ifosfamide in hepatocellular carcinoma.

Authors:  J Lin; W Shiu; W T Leung; M Tao; N Leung; W Y Lau; A K Li
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

Review 2.  Epirubicin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in cancer chemotherapy.

Authors:  G L Plosker; D Faulds
Journal:  Drugs       Date:  1993-05       Impact factor: 9.546

3.  Treatment of inoperable hepatocellular carcinoma by intra-arterial lipiodol and 4'-epidoxorubicin.

Authors:  W T Leung; W C Shiu; N Leung; M Chan; M Tao; A K Li; C Metreweli
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

  3 in total

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