Literature DB >> 28423010

Correction: The H3K27 demethylase, Utx, regulates adipogenesis in a differentiation stage-dependent manner.

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Abstract

[This corrects the article DOI: 10.1371/journal.pone.0173713.].

Entities:  

Year:  2017        PMID: 28423010      PMCID: PMC5397054          DOI: 10.1371/journal.pone.0176424

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


The arrows are missing from Fig 5E. The publisher apologizes for the error. Please see the corrected Fig 5 here.
Fig 5

Knockdown of Utx in 3T3-L1 cells resulted in an enhancement of adipocyte differentiation.

(A) Oil-red O staining of adipocytes. Representative results from three independent experiments are shown. mRNA levels of (B) Utx, (C) C/EBP alpha, Pparg2, (D) Pparg2 normalized to β-actin. The experiments were performed independently three times in triplicates and the representative results are shown and expressed as mean ± SE. (n = 3) *p<0.05. (E) Schematic model of Utx during differentiation of mESCs to adipocytes.

Knockdown of Utx in 3T3-L1 cells resulted in an enhancement of adipocyte differentiation.

(A) Oil-red O staining of adipocytes. Representative results from three independent experiments are shown. mRNA levels of (B) Utx, (C) C/EBP alpha, Pparg2, (D) Pparg2 normalized to β-actin. The experiments were performed independently three times in triplicates and the representative results are shown and expressed as mean ± SE. (n = 3) *p<0.05. (E) Schematic model of Utx during differentiation of mESCs to adipocytes.
  1 in total

1.  The H3K27 demethylase, Utx, regulates adipogenesis in a differentiation stage-dependent manner.

Authors:  Kazushige Ota; Kit I Tong; Kouichiro Goto; Shuta Tomida; Akiyoshi Komuro; Zhong Wang; Kazuto Nishio; Hitoshi Okada
Journal:  PLoS One       Date:  2017-03-20       Impact factor: 3.240

  1 in total

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