Literature DB >> 2842191

Superoxide production from nonenzymatically glycated protein.

T Sakurai1, S Tsuchiya.   

Abstract

Nonenzymatically glycated human serum albumin and glycated poly-lysine(Lys) in vitro brought about the reduction of nitroblue tetrazolium and ferricytochrome c at pH 9.06 and pH 7.8, respectively. This reduction was inhibited partially by superoxide dismutase (SOD). Glycated poly-Lys caused the oxidation of NADH in the presence of LDH at pH 7.0 which was completely inhibited by SOD. Glycated material was found to function both as a reductant and an oxidant. The reactivity of glycated material is discussed and a possible mechanism by which superoxide is produced is proposed. Results may give a clue to diabetic complications.

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Year:  1988        PMID： 2842191     DOI： 10.1016/0014-5793(88)80066-8

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  37 in total

1.  Alterations in tissue glutathione antioxidant system in streptozotocin-induced diabetic rats.

Authors:  D H Mak; S P Ip; P C Li; M K Poon; K M Ko
Journal:  Mol Cell Biochem       Date:  1996-09-20       Impact factor: 3.396

2.  Reducing sugars trigger oxidative modification and apoptosis in pancreatic beta-cells by provoking oxidative stress through the glycation reaction.

Authors:  H Kaneto; J Fujii; T Myint; N Miyazawa; K N Islam; Y Kawasaki; K Suzuki; M Nakamura; H Tatsumi; Y Yamasaki; N Taniguchi
Journal:  Biochem J       Date:  1996-12-15       Impact factor: 3.857

3.  Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells.

Authors:  T Matsuoka; Y Kajimoto; H Watada; H Kaneto; M Kishimoto; Y Umayahara; Y Fujitani; T Kamada; R Kawamori; Y Yamasaki
Journal:  J Clin Invest       Date:  1997-01-01       Impact factor: 14.808

Review 4.  Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis.

Authors:  Hideaki Kaneto; Naoto Katakami; Munehide Matsuhisa; Taka-aki Matsuoka
Journal:  Mediators Inflamm       Date:  2010-02-16       Impact factor: 4.711

5.  Protective influence of vitamin E on the antioxidant defence system in the whole blood and liver of normal and alloxan-induced diabetic rats.

Authors:  J O Olanlokun
Journal:  Indian J Clin Biochem       Date:  2008-03-06

6.  Ribosylation of bovine serum albumin induces ROS accumulation and cell death in cancer line (MCF-7).

Authors:  Mohd Shahnawaz Khan; Sourabh Dwivedi; Medha Priyadarshini; Shams Tabrez; Maqsood Ahmed Siddiqui; Haseeb Jagirdar; Abdulrahman M Al-Senaidy; Abdulaziz A Al-Khedhairy; Javed Musarrat
Journal:  Eur Biophys J       Date:  2013-11-12       Impact factor: 1.733

7.  Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes.

Authors:  A M Schmidt; O Hori; J X Chen; J F Li; J Crandall; J Zhang; R Cao; S D Yan; J Brett; D Stern
Journal:  J Clin Invest       Date:  1995-09       Impact factor: 14.808

8.  LR-90 a new advanced glycation endproduct inhibitor prevents progression of diabetic nephropathy in streptozotocin-diabetic rats.

Authors:  J L Figarola; S Scott; S Loera; C Tessler; P Chu; L Weiss; J Hardy; S Rahbar
Journal:  Diabetologia       Date:  2003-07-05       Impact factor: 10.122

Review 9.  Understanding Genetic Heterogeneity in Type 2 Diabetes by Delineating Physiological Phenotypes: SIRT1 and its Gene Network in Impaired Insulin Secretion.

Authors:  Shafat Ali; Shazia Nafis; Ponnusamy Kalaiarasan; Ekta Rai; Swarkar Sharma; Rameshwar N Bamezai
Journal:  Rev Diabet Stud       Date:  2016-05-10

Review 10.  Diabetes and Its Effect on Bone and Fracture Healing.

Authors:  Hongli Jiao; E Xiao; Dana T Graves
Journal:  Curr Osteoporos Rep       Date:  2015-10       Impact factor: 5.096
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