Literature DB >> 28421776

Drugs via enteral feeding tubes in inpatients: dispersion analysis and safe use of dispensers.

Milena Pontes Portela Beserra1, Cristiani Lopes Capistrano Gonçalves De Oliveira, Mileyde Ponte Portela, Marcos Venícios de Oliveira Lopes, Marta Maria de França Fonteles.   

Abstract

OBJECTIVE: This study aimed to improve knowledge about drug administration through enteral feeding tubes (EFTs) in order to minimize efficacy and safety problems.
MATERIAL AND METHODS: The study was performed in a public secondary care hospital with level II accreditation by the National Accreditation Organization (Organização Nacional de Acreditação ONA), in Fortaleza, Ceará, north-eastern Brazil.
RESULTS: One hundred and eight oral solid medications that could be administered through EFTs and were not available in liquid forms were evaluated via transformation of their solid dosage forms into liquid forms. Dispersion times and conditions were assessed to determine which medications should be crushed. We compared the use of dispensers and syringes and their connections to enteral feeding tubes and intravenous devices. Medications whose dispersion occurred within 20 minutes and could be visually perceived and whose content could be expelled without occluding the oral syringe were considered "satisfactory".
CONCLUSIONS: The dispersion was "satisfactory" in 82 (75.9%) of the medications; they were classified as capable of being dispersed in water in the oral syringe for further administration via EFTs without the need for crushing. Use the dispenser instead of the syringe for drug administration was safer because the dispenser apparatus did not fit into equipment for intravenous drug administration.

Entities:  

Keywords:  Tablets. Capsules. Enteral nutrition. Drug administration routes. Patient safety.

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Substances:

Year:  2017        PMID: 28421776     DOI: 10.20960/nh.486

Source DB:  PubMed          Journal:  Nutr Hosp        ISSN: 0212-1611            Impact factor:   1.057


  1 in total

1.  An Ex Vivo Evaluation of Cenobamate Administered via Enteral Tubes.

Authors:  Louis Ferrari; Arkady Nisman; Augustin Pegan; Jordan Ursino
Journal:  Drugs R D       Date:  2020-06
  1 in total

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