| Literature DB >> 28421763 |
Andrew C Flick1, Hong X Ding2, Carolyn A Leverett1, Robert E Kyne3, Kevin K-C Liu4, Sarah J Fink5, Christopher J O'Donnell1.
Abstract
New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition while serving as leads for designing future new drugs. This annual review describes the most likely process-scale synthetic approaches to 29 new chemical entities (NCEs) that were approved for the first time in 2015.Mesh：
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Year: 2017 PMID： 28421763 DOI： 10.1021/acs.jmedchem.7b00010
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446