Literature DB >> 28421446

PRE/TRE elements act as transcription activators in Drosophila S2 Cells.

D A Chetverina1, A V Mikhailova1, P G Georgiev1, M M Erokhin2.   

Abstract

The Drosophila PRE/TRE elements are DNA targets for Polycomb and Trithorax group proteins, which control repression and activation of gene transcription, respectively. In this study, we show that, in transiently transfected Drosophila S2 cells, bxdPRE activates transcription driven from different promoters. Using CG32795 gene promoter, we demonstrate that other PRE/TRE elements-Fab7, en, eve, and CycB-also act as transcription activators in this model system.

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Year:  2017        PMID: 28421446     DOI: 10.1134/S1607672917010161

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN: 1607-6729            Impact factor:   0.788


  11 in total

Review 1.  Trithorax group proteins: switching genes on and keeping them active.

Authors:  Bernd Schuettengruber; Anne-Marie Martinez; Nicola Iovino; Giacomo Cavalli
Journal:  Nat Rev Mol Cell Biol       Date:  2011-11-23       Impact factor: 94.444

2.  Creation of a new system to study insulators in Drosophila melanogaster.

Authors:  M M Erokhin; P G Georgiev; D A Chetverina
Journal:  Dokl Biochem Biophys       Date:  2009 Sep-Oct       Impact factor: 0.788

Review 3.  Trithorax and Polycomb group-dependent regulation: a tale of opposing activities.

Authors:  Sarah J Geisler; Renato Paro
Journal:  Development       Date:  2015-09-01       Impact factor: 6.868

Review 4.  Biochemical mechanisms of gene regulation by polycomb group protein complexes.

Authors:  Jürg Müller; Peter Verrijzer
Journal:  Curr Opin Genet Dev       Date:  2009-04-01       Impact factor: 5.578

Review 5.  Transcriptional regulation by Polycomb group proteins.

Authors:  Luciano Di Croce; Kristian Helin
Journal:  Nat Struct Mol Biol       Date:  2013-10       Impact factor: 15.369

Review 6.  Silencing chromatin: comparing modes and mechanisms.

Authors:  Christian Beisel; Renato Paro
Journal:  Nat Rev Genet       Date:  2011-01-11       Impact factor: 53.242

Review 7.  Perspectives on the RNA polymerase II core promoter.

Authors:  James T Kadonaga
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2011-12-06       Impact factor: 5.814

8.  Transcriptional read-through is not sufficient to induce an epigenetic switch in the silencing activity of Polycomb response elements.

Authors:  Maksim Erokhin; Pavel Elizar'ev; Aleksander Parshikov; Paul Schedl; Pavel Georgiev; Darya Chetverina
Journal:  Proc Natl Acad Sci U S A       Date:  2015-10-26       Impact factor: 11.205

Review 9.  Are we there yet? Initial targeting of the Male-Specific Lethal and Polycomb group chromatin complexes in Drosophila.

Authors:  Kyle A McElroy; Hyuckjoon Kang; Mitzi I Kuroda
Journal:  Open Biol       Date:  2014-03-26       Impact factor: 6.411

10.  Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.

Authors:  A H Brand; N Perrimon
Journal:  Development       Date:  1993-06       Impact factor: 6.868

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