Literature DB >> 28419327

Epilepsy Surgeries Requiring an Operculoinsular Cortectomy: Operative Technique and Results.

Alain Bouthillier1, Dang Khoa Nguyen2.   

Abstract

BACKGROUND: Epilepsy surgeries requiring an operculoinsulectomy pose significant difficulties because the perisylvian area is highly vascular, deep, and functional.
OBJECTIVE: To report the operative technique and results of epilepsy surgeries requiring an operculoinsular cortectomy at our institution.
METHODS: The data of all consecutive patients who had undergone an epilepsy surgery requiring an operculoinsular cortectomy with a minimum follow-up of 1 yr were reviewed. Tumor and vascular malformation cases were excluded. Surgical techniques are described based on findings during surgery.
RESULTS: Twenty-five patients underwent an epilepsy surgery requiring an operculoinsular cortectomy: mean age at surgery was 35 y (9-51), mean duration of epilepsy was 19 y (5-36), 14 were female, and mean duration of follow-up was 4.7 y (1-16). Magnetic resonance imaging of the operculoinsular area was normal or revealed questionable nonspecific findings in 72% of cases. Investigation with intracranial EEG electrodes was done in 17 patients. Surgery was performed on the dominant side for language in 7 patients. An opercular resection was performed in all but 2 patients who only had an insulectomy. Engel class I seizure control was achieved in 80% of patients. Postoperative neurological deficits (paresis, dysphasia, alteration of taste, smell, hearing, pain, and thermal perceptions) were frequent (75%) but always transient except for 1 patient with persistent mild alteration of thermal and pain perception.
CONCLUSION: Surgical treatment of operculoinsular epilepsy is effective in achieving seizure control and is associated with an acceptable long-term complication rate.
Copyright © 2017 by the Congress of Neurological Surgeons

Entities:  

Keywords:  Cortectomy; Insula; Operculum; Perisylvian epilepsy; Refractory epilepsy; Surgery

Mesh:

Year:  2017        PMID: 28419327     DOI: 10.1093/neuros/nyx080

Source DB:  PubMed          Journal:  Neurosurgery        ISSN: 0148-396X            Impact factor:   4.654


  7 in total

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6.  Cortical thickness analysis in operculo-insular epilepsy.

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7.  A new role of 11 C-Choline PET in localizing the epileptogenic foci in insular cortex in the patients.

Authors:  Yu-Feng Chen; Ran Wei; Guan-Qian Yuan; Dan-Dan Gao; Qing Jin; Xiao-Yu Cui; Guo-Xu Zhang; Jia Guo
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  7 in total

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