| Literature DB >> 28416538 |
Enrica Mello1, Brunella Posteraro2, Antonietta Vella1, Elena De Carolis1, Riccardo Torelli1, Tiziana D'Inzeo1, Paul E Verweij3, Maurizio Sanguinetti4.
Abstract
We tested 59 common and 27 uncommon Aspergillus species isolates for susceptibility to the mold-active azole antifungal agents itraconazole, voriconazole, and posaconazole using the Sensititre method. The overall essential agreement with the CLSI reference method was 96.5% for itraconazole and posaconazole and was 100% for voriconazole. By the Sensititre method as well as the CLSI reference method, all of 10 A. fumigatus isolates with a cyp51 mutant genotype were classified as being non-wild-type isolates (MIC > epidemiological cutoff value [ECV]) with respect to triazole susceptibility.Entities:
Keywords: Aspergillus; Sensititre; antifungal susceptibility testing
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Year: 2017 PMID: 28416538 PMCID: PMC5444134 DOI: 10.1128/AAC.00168-17
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191