| Literature DB >> 28416267 |
Vivian Klungboonkrong1, Dola Das2, Gordon McLennan3.
Abstract
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. HCC develops through a multistep process that involves the local tumor microenvironment, intracellular signaling pathways, and altered metabolic system that allows the cancer proliferation. Understanding the mechanisms of tumor development and progression is critical to developing improved therapies aimed at better survival. This article reviews the molecular mechanisms of HCC development and highlights the potential therapeutic targets for treatments.Entities:
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Year: 2017 PMID： 28416267 DOI： 10.1016/j.jvir.2017.03.002
Source DB: PubMed Journal: J Vasc Interv Radiol ISSN： 1051-0443 Impact factor: 3.464