Literature DB >> 28414653

Increasing value and reducing waste in stroke research.

Eivind Berge1, Rustam Al-Shahi Salman2, H Bart van der Worp3, Christian Stapf4, Peter Sandercock2, Nikola Sprigg5, Malcolm R Macleod2, Peter J Kelly6, Paul J Nederkoorn7, Gary A Ford8.   

Abstract

Stroke is a major burden to patients and society, and resources spent on stroke research must be used efficiently and produce good value in terms of improvements in human health. However, many instances of poor value from stroke research funding have resulted from the way in which stroke research topics have been chosen and how studies have been designed, conducted, analysed, regulated, managed, disseminated, or reported. A cooperative effort of European stroke researchers aimed to identify sources of inefficiency and waste, recommend approaches to increase value, and highlight examples of best practice in stroke research. Evidence suggests that progress has been made, but there is room for much improvement; researchers, funders, regulators, and other stakeholders in stroke research might consider these recommendations when planning new research.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID: 28414653     DOI: 10.1016/S1474-4422(17)30078-9

Source DB:  PubMed          Journal:  Lancet Neurol        ISSN: 1474-4422            Impact factor:   44.182


  15 in total

Review 1.  Variability of functional outcome measures used in animal models of stroke and vascular cognitive impairment - a review of contemporary studies.

Authors:  Tuuli M Hietamies; Caroline Ostrowski; Zhong Pei; Luyang Feng; Christopher McCabe; Lorraine M Work; Terence J Quinn
Journal:  J Cereb Blood Flow Metab       Date:  2018-09-11       Impact factor: 6.200

Review 2.  Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function.

Authors:  Alanna G Spiteri; Claire L Wishart; Roger Pamphlett; Giuseppe Locatelli; Nicholas J C King
Journal:  Acta Neuropathol       Date:  2021-12-01       Impact factor: 17.088

3.  Brief Consent Methods Enable Rapid Enrollment in Acute Stroke Trial: Results From the TICH-2 Randomized Controlled Trial.

Authors:  Zhe Kang Law; Jason P Appleton; Polly Scutt; Ian Roberts; Rustam Al-Shahi Salman; Timothy J England; David J Werring; Thompson Robinson; Kailash Krishnan; Robert A Dineen; Ann Charlotte Laska; Philippe A Lyrer; Juan Jose Egea-Guerrero; Michal Karlinski; Hanne Christensen; Christine Roffe; Daniel Bereczki; Serefnur Ozturk; Jegan Thanabalan; Ronan Collins; Maia Beridze; Alfonso Ciccone; Lelia Duley; Angela Shone; Philip M Bath; Nikola Sprigg
Journal:  Stroke       Date:  2021-12-01       Impact factor: 7.914

Review 4.  Conservative interventions for treating urinary incontinence in women: an Overview of Cochrane systematic reviews.

Authors:  Alex Todhunter-Brown; Christine Hazelton; Pauline Campbell; Andrew Elders; Suzanne Hagen; Doreen McClurg
Journal:  Cochrane Database Syst Rev       Date:  2022-09-02

5.  Building a European 'network of networks' for stroke clinical research - The European Stroke Organisation Trials Alliance (ESOTA).

Authors:  Peter Kelly; Rustam A Salman; Anita Arsovska; Diederik Wj Dippel; Urs Fischer; Gary A Ford; Blanca Fuentes; Robin Lemmens; John C Marshall; Paul J Nederkoorn; Thompson Robinson; Christian Weimar; Eivind Berge
Journal:  Eur Stroke J       Date:  2019-05-07

Review 6.  Impact of aging and comorbidities on ischemic stroke outcomes in preclinical animal models: A translational perspective.

Authors:  Eduardo Candelario-Jalil; Surojit Paul
Journal:  Exp Neurol       Date:  2020-10-07       Impact factor: 5.330

7.  Translational Block in Stroke: A Constructive and "Out-of-the-Box" Reappraisal.

Authors:  Athanasios Lourbopoulos; Iordanis Mourouzis; Christodoulos Xinaris; Nefeli Zerva; Konstantinos Filippakis; Angelos Pavlopoulos; Constantinos Pantos
Journal:  Front Neurosci       Date:  2021-05-14       Impact factor: 4.677

8.  Preventive psychiatry: a blueprint for improving the mental health of young people.

Authors:  Paolo Fusar-Poli; Christoph U Correll; Celso Arango; Michael Berk; Vikram Patel; John P A Ioannidis
Journal:  World Psychiatry       Date:  2021-06       Impact factor: 79.683

9.  How novice, skilled and advanced clinical researchers include variables in a case report form for clinical research: a qualitative study.

Authors:  Hongling Chu; Lin Zeng; Micheal D Fetters; Nan Li; Liyuan Tao; Yanyan Shi; Hua Zhang; Xiaoxiao Wang; Fengwei Li; Yiming Zhao
Journal:  BMJ Open       Date:  2017-09-18       Impact factor: 2.692

10.  Establishing research priorities relating to the long-term impact of TIA and minor stroke through stakeholder-centred consensus.

Authors:  Grace M Turner; Ruth Backman; Christel McMullan; Jonathan Mathers; Tom Marshall; Melanie Calvert
Journal:  Res Involv Engagem       Date:  2018-01-25
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