Literature DB >> 28414051

Mechanisms contributing to cognitive deficits in cannabis users.

Romina Mizrahi1, Jeremy J Watts2, Kuei Y Tseng3.   

Abstract

Studies from preclinical animal models indicate that sustained activation of CB1 receptor signaling is a major contributing factor for the onset of cognitive deficits associated to chronic cannabis use, in particular within the working memory and decision-making domains. Yet, very few studies have been designed to directly assess the role of CB1 receptors in mediating the effects of cannabis on human brain function. This perspective review article provides an overview of current state of knowledge on possible neurobiological mechanisms accounting for the detrimental effects of chronic cannabis use on cognition and related changes in brain structure and functional connectivity. This article is part of the Special Issue entitled "A New Dawn in Cannabinoid Neurobiology".
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  CB1 receptors; Cannabinoids; Cannabis; Cognition; Connectivity; Imaging; Prefrontal cortex; THC

Mesh：

Substances：

Year:  2017        PMID： 28414051      PMCID： PMC5540783          DOI： 10.1016/j.neuropharm.2017.04.018

Source DB:  PubMed          Journal:  Neuropharmacology        ISSN： 0028-3908            Impact factor:   5.250


  61 in total

1.  Neuropsychological performance in long-term cannabis users.

Authors:  H G Pope; A J Gruber; J I Hudson; M A Huestis; D Yurgelun-Todd
Journal:  Arch Gen Psychiatry       Date:  2001-10

2.  Residual effects of cannabis use on neurocognitive performance after prolonged abstinence: a meta-analysis.

Authors:  Amy M Schreiner; Michael E Dunn
Journal:  Exp Clin Psychopharmacol       Date:  2012-06-25       Impact factor: 3.157

3.  Gross morphological brain changes with chronic, heavy cannabis use.

Authors:  Valentina Lorenzetti; Nadia Solowij; Sarah Whittle; Alex Fornito; Dan I Lubman; Christos Pantelis; Murat Yücel
Journal:  Br J Psychiatry       Date:  2014-11-27       Impact factor: 9.319

4.  Effects of δ9-tetrahydrocannabinol on human working memory function.

Authors:  Matthijs G Bossong; J Martijn Jansma; Hendrika H van Hell; Gerry Jager; Erik Oudman; Emi Saliasi; René S Kahn; Nick F Ramsey
Journal:  Biol Psychiatry       Date:  2012-02-17       Impact factor: 13.382

Review 5.  Neural bases of learning and memory: functional neuroimaging evidence.

Authors:  R Cabeza; L Nyberg
Journal:  Curr Opin Neurol       Date:  2000-08       Impact factor: 5.710

Review 6.  The Role of Cannabinoids in Neuroanatomic Alterations in Cannabis Users.

Authors:  Valentina Lorenzetti; Nadia Solowij; Murat Yücel
Journal:  Biol Psychiatry       Date:  2015-12-04       Impact factor: 13.382

7.  Rapid Changes in CB1 Receptor Availability in Cannabis Dependent Males after Abstinence from Cannabis.

Authors:  Deepak Cyril D'Souza; Jose A Cortes-Briones; Mohini Ranganathan; Halle Thurnauer; Gina Creatura; Toral Surti; Beata Planeta; Alexander Neumeister; Brian Pittman; Marc Normandin; Michael Kapinos; Jim Ropchan; Yiyun Huang; Richard E Carson; Patrick D Skosnik
Journal:  Biol Psychiatry Cogn Neurosci Neuroimaging       Date:  2016-01-01

8.  Effects of 7 days of treatment with the cannabinoid type 1 receptor antagonist, rimonabant, on emotional processing.

Authors:  Jamie Horder; Michael Browning; Martina Di Simplicio; Philip J Cowen; Catherine J Harmer
Journal:  J Psychopharmacol       Date:  2011-03-15       Impact factor: 4.153

Review 9.  Role of endogenous cannabinoids in synaptic signaling.

Authors:  Tamas F Freund; Istvan Katona; Daniele Piomelli
Journal:  Physiol Rev       Date:  2003-07       Impact factor: 37.312

Review 10.  Effect of cannabis on glutamate signalling in the brain: A systematic review of human and animal evidence.

Authors:  Marco Colizzi; Philip McGuire; Roger G Pertwee; Sagnik Bhattacharyya
Journal:  Neurosci Biobehav Rev       Date:  2016-03-14       Impact factor: 8.989
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  6 in total

1.  In Vivo Imaging of Translocator Protein in Long-term Cannabis Users.

Authors:  Tania Da Silva; Sina Hafizi; Jeremy J Watts; Cynthia Shannon Weickert; Jeffrey H Meyer; Sylvain Houle; Pablo Rusjan; Romina Mizrahi
Journal:  JAMA Psychiatry       Date:  2019-12-01       Impact factor: 21.596

2.  Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells.

Authors:  Liliana Galindo; Estefanía Moreno; Fernando López-Armenta; Daniel Guinart; Aida Cuenca-Royo; Mercè Izquierdo-Serra; Laura Xicota; Cristina Fernandez; Esther Menoyo; José M Fernández-Fernández; Gloria Benítez-King; Enric I Canela; Vicent Casadó; Víctor Pérez; Rafael de la Torre; Patricia Robledo
Journal:  Mol Neurobiol       Date:  2018-01-02       Impact factor: 5.590

3.  Altered Corticolimbic Control of the Nucleus Accumbens by Long-term Δ9-Tetrahydrocannabinol Exposure.

Authors:  Eun-Kyung Hwang; Carl R Lupica
Journal:  Biol Psychiatry       Date:  2019-08-06       Impact factor: 13.382

4.  Psychotic experiences and subjective cognitive complaints among 224 842 people in 48 low- and middle-income countries.

Authors:  A Koyanagi; B Stubbs; E Lara; N Veronese; D Vancampfort; L Smith; J M Haro; H Oh; J E DeVylder
Journal:  Epidemiol Psychiatr Sci       Date:  2018-12-26       Impact factor: 6.892

5.  Functional brain connectomes reflect acute and chronic cannabis use.

Authors:  J G Ramaekers; N L Mason; S W Toennes; E L Theunissen; E Amico
Journal:  Sci Rep       Date:  2022-02-14       Impact factor: 4.379

6.  Cannabis increases susceptibility to false memory.

Authors:  Lilian Kloft; Henry Otgaar; Arjan Blokland; Lauren A Monds; Stefan W Toennes; Elizabeth F Loftus; Johannes G Ramaekers
Journal:  Proc Natl Acad Sci U S A       Date:  2020-02-10       Impact factor: 11.205
  6 in total

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