Literature DB >> 28413951

An Unprecedented Revolution in Medicinal Chemistry Driven by the Progress of Biological Science.

Kuo-Chen Chou1.   

Abstract

The eternal or ultimate goal of medicinal chemistry is to find most effective ways to treat various diseases and extend human beings' life as long as possible. Human being is a biological entity. To realize such an ultimate goal, the inputs or breakthroughs from the advances in biological science are no doubt most important that may even drive medicinal science into a revolution. In this review article, we are to address this from several different angles. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Biomacromolecules; Encephalomyopathy; Low-frequency internal motions; Oligomerizes; PseAAC/PseKNC; Transmembrane; Viroporin; Web-server

Mesh：

Substances：

Year:  2017        PMID： 28413951     DOI： 10.2174/1568026617666170414145508

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN： 1568-0266            Impact factor:   3.295


  40 in total

1.  iN6-methylat (5-step): identifying DNA N6-methyladenine sites in rice genome using continuous bag of nucleobases via Chou's 5-step rule.

Authors:  Nguyen Quoc Khanh Le
Journal:  Mol Genet Genomics       Date:  2019-05-04       Impact factor: 3.291

2.  iPhosY-PseAAC: identify phosphotyrosine sites by incorporating sequence statistical moments into PseAAC.

Authors:  Yaser Daanial Khan; Nouman Rasool; Waqar Hussain; Sher Afzal Khan; Kuo-Chen Chou
Journal:  Mol Biol Rep       Date:  2018-10-11       Impact factor: 2.316

3.  MULTiPly: a novel multi-layer predictor for discovering general and specific types of promoters.

Authors:  Meng Zhang; Fuyi Li; Tatiana T Marquez-Lago; André Leier; Cunshuo Fan; Chee Keong Kwoh; Kuo-Chen Chou; Jiangning Song; Cangzhi Jia
Journal:  Bioinformatics       Date:  2019-09-01       Impact factor: 6.937

4.  Predicting membrane proteins and their types by extracting various sequence features into Chou's general PseAAC.

Authors:  Ahmad Hassan Butt; Nouman Rasool; Yaser Daanial Khan
Journal:  Mol Biol Rep       Date:  2018-09-20       Impact factor: 2.316

Review 5.  Structural Variability in the RLR-MAVS Pathway and Sensitive Detection of Viral RNAs.

Authors:  Qiu-Xing Jiang
Journal:  Med Chem       Date:  2019       Impact factor: 2.745

6.  Mal-Light: Enhancing Lysine Malonylation Sites Prediction Problem Using Evolutionary-based Features.

Authors:  Wakil Ahmad; Easin Arafat; Ghazaleh Taherzadeh; Alok Sharma; Shubhashis Roy Dipta; Abdollah Dehzangi; Swakkhar Shatabda
Journal:  IEEE Access       Date:  2020-04-22       Impact factor: 3.367

Review 7.  Some illuminating remarks on molecular genetics and genomics as well as drug development.

Authors:  Kuo-Chen Chou
Journal:  Mol Genet Genomics       Date:  2020-01-01       Impact factor: 3.291

8.  Structural insights of dipeptidyl peptidase-IV inhibitors through molecular dynamics-guided receptor-dependent 4D-QSAR studies.

Authors:  Rajesh B Patil; Euzebio G Barbosa; Jaiprakash N Sangshetti; Vishal P Zambre; Sanjay D Sawant
Journal:  Mol Divers       Date:  2018-03-13       Impact factor: 2.943

9.  PScL-HDeep: image-based prediction of protein subcellular location in human tissue using ensemble learning of handcrafted and deep learned features with two-layer feature selection.

Authors:  Matee Ullah; Ke Han; Fazal Hadi; Jian Xu; Jiangning Song; Dong-Jun Yu
Journal:  Brief Bioinform       Date:  2021-11-05       Impact factor: 13.994

10.  Assessing the Performances of Protein Function Prediction Algorithms from the Perspectives of Identification Accuracy and False Discovery Rate.

Authors:  Chun Yan Yu; Xiao Xu Li; Hong Yang; Ying Hong Li; Wei Wei Xue; Yu Zong Chen; Lin Tao; Feng Zhu
Journal:  Int J Mol Sci       Date:  2018-01-08       Impact factor: 5.923
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