Literature DB >> 28413551

Alveolar soft part sarcoma with brain metastases.

Vinodh Vayara Perumall1, Rahmat Harun1, Pulivendhan Sellamuthu1, Mohd Shariman Md Shah2.   

Abstract

Metastatic tumors are the most common mass lesions in the brain. This case reports a rare form of sarcoma with metastasis to the brain. The appropriate management of a patient with metastatic alveolar soft part sarcoma to the brain is discussed. Author describes a 32-year-old gentleman diagnosed with primary tumor at gluteus and distant metastases at lower lobe of right lung and the brain. Histopathology proves diagnosis as alveolar soft part sarcoma. Craniotomy with excision of brain lesion was done. Repeated magnetic resonance imaging of the brain after 2 months showed rapidly growing new lesions. The next step of management was made by the oncology team as recurrence rate was high and due to multi-systemic involvement. Patient was planned for palliative chemotherapy and to be reassessed later. This case report discusses the appropriate approach to any form of brain metastases and the role of early follow-up especially after surgery for better outcome and choice of post operative management such as radiotherapy or chemotherapy or both for malignant tumors. Based on this report, it was concluded that every brain tumor patient should be frequently monitored even in the outpatient setting as most of them are metastatic and rapidly spreading. The patient should be considered for radiotherapy or chemotherapy or both after surgery if the histopathology result is suggestive of malignancy.

Entities:  

Keywords:  Alveolar soft part sarcoma; brain metastases; central nervous system neoplasm; combined therapy; tumor recurrence

Year:  2017        PMID: 28413551      PMCID: PMC5379782          DOI: 10.4103/1793-5482.144197

Source DB:  PubMed          Journal:  Asian J Neurosurg


  14 in total

1.  Alveolar soft-part sarcoma presenting with eosinophilia and shunt.

Authors:  M Almansori; A R Turner; S Girgis; D Vethanayagam
Journal:  Can Respir J       Date:  2005-10       Impact factor: 2.409

2.  Surgery for multiple lung metastases from alveolar soft-part sarcoma.

Authors:  K Kodama; O Doi; M Higashiyama; H Yokouchi; K Kuriyama; T Ueda; H Yoshikawa
Journal:  Surg Today       Date:  1997       Impact factor: 2.549

3.  Alveolar soft part sarcoma: a rare and enigmatic entity.

Authors:  Megan E Anderson; Francis J Hornicek; Mark C Gebhardt; Kevin A Raskin; Henry J Mankin
Journal:  Clin Orthop Relat Res       Date:  2005-09       Impact factor: 4.176

4.  Prolonged survival after bilateral thoracotomy for metastatic alveolar soft-part sarcoma.

Authors:  T M Berman; S A Fuhrman; F E Johnson
Journal:  Minn Med       Date:  1984-05

5.  Sarcoma metastatic to the brain: results of surgical treatment.

Authors:  R K Bindal; R E Sawaya; M E Leavens; S H Taylor; V F Guinee
Journal:  Neurosurgery       Date:  1994-08       Impact factor: 4.654

6.  Alveolar soft-part sarcoma responsive to intensive chemotherapy.

Authors:  H James Nickerson; Teresa Silberman; F Stig Jacobsen; Bruce R Krawisz; Hope S Maki; Carola A S Arndt
Journal:  J Pediatr Hematol Oncol       Date:  2004-04       Impact factor: 1.289

7.  Alveolar soft part sarcoma: clinical course and patterns of metastasis in 70 patients treated at a single institution.

Authors:  C A Portera ; V Ho; S R Patel; K K Hunt; B W Feig; P M Respondek; A W Yasko; R S Benjamin; R E Pollock; P W Pisters
Journal:  Cancer       Date:  2001-02-01       Impact factor: 6.860

8.  The choice of treatment of single brain metastasis should be based on extracranial tumor activity and age.

Authors:  E M Noordijk; C J Vecht; H Haaxma-Reiche; G W Padberg; J H Voormolen; F H Hoekstra; J T Tans; N Lambooij; J A Metsaars; A R Wattendorff
Journal:  Int J Radiat Oncol Biol Phys       Date:  1994-07-01       Impact factor: 7.038

9.  Alveolar soft part sarcoma of the head and neck. A disease of children and young adults.

Authors:  W B Simmons; H S Haggerty; B Ngan; C K Anonsen
Journal:  Int J Pediatr Otorhinolaryngol       Date:  1989-05       Impact factor: 1.675

10.  Alveolar soft part sarcoma in children and adolescents: clinical features and outcome of 11 patients.

Authors:  A S Pappo; D M Parham; A Cain; X Luo; L C Bowman; W L Furman; B N Rao; C B Pratt
Journal:  Med Pediatr Oncol       Date:  1996-02
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  1 in total

1.  Alveolar Soft Part Sarcoma Metastasizing to the Brain: A Rare Entity Revisited with Review of Recent Literature.

Authors:  Singh Mathuria Kaushal-Deep; Uday Singh Raswan; Altaf Rehman Kirmani; Abdul Rashid Bhat; Irfan Hussain Bhat
Journal:  J Pediatr Neurosci       Date:  2019-09-27
  1 in total

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