Literature DB >> 28412184

Clinical trial research in focus: why do so many clinical trials fail in IPF?

Paolo Spagnolo1, Toby M Maher2.   

Abstract

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Year:  2017        PMID： 28412184     DOI： 10.1016/S2213-2600(17)30122-4

Source DB:  PubMed          Journal:  Lancet Respir Med        ISSN： 2213-2600            Impact factor:   30.700


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  10 in total

1.  New Applications of Old Drugs as Novel Therapies in Idiopathic Pulmonary Fibrosis. Metformin, Hydroxychloroquine, and Thyroid Hormone.

Authors:  Edward P Manning; Ashley Losier; Nkiruka Emeagwali; Changwan Ryu; Shyoko Honiden
Journal:  Am J Respir Crit Care Med       Date:  2019-06-15       Impact factor: 21.405

2.  TREAP: A New Topological Approach to Drug Target Inference.

Authors:  Muying Wang; Lauren L Luciani; Heeju Noh; Ericka Mochan; Jason E Shoemaker
Journal:  Biophys J       Date:  2020-10-29       Impact factor: 4.033

3.  Intracellular hydroxyproline imprinting following resolution of bleomycin-induced pulmonary fibrosis.

Authors:  Shengren Song; Zhenli Fu; Ruijuan Guan; Jie Zhao; Penghui Yang; Yang Li; Hang Yin; Yunxin Lai; Gencheng Gong; Simin Zhao; Jiangtian Yu; Xiaomin Peng; Ying He; Yumei Luo; Nanshan Zhong; Jin Su
Journal:  Eur Respir J       Date:  2022-05-05       Impact factor: 33.795

4.  Synergistic application of pulmonary 18F-FDG PET/HRCT and computer-based CT analysis with conventional severity measures to refine current risk stratification in idiopathic pulmonary fibrosis (IPF).

Authors:  Francesco Fraioli; Maria Lyasheva; Joanna C Porter; Jamshed Bomanji; Robert I Shortman; Raymond Endozo; Simon Wan; Linda Bertoletti; Maria Machado; Balaji Ganeshan; Thida Win; Ashley M Groves
Journal:  Eur J Nucl Med Mol Imaging       Date:  2019-07-08       Impact factor: 9.236

5.  Telehealth for patients with interstitial lung diseases (ILD): results of an international survey of clinicians.

Authors:  Malik Althobiani; Jaber S Alqahtani; John R Hurst; Anne-Marie Russell; Joanna Porter
Journal:  BMJ Open Respir Res       Date:  2021-12

6.  A scalable 3D tissue culture pipeline to enable functional therapeutic screening for pulmonary fibrosis.

Authors:  Katherine A Cummins; Peter B Bitterman; Daniel J Tschumperlin; David K Wood
Journal:  APL Bioeng       Date:  2021-11-16

Review 7.  Home monitoring of physiology and symptoms to detect interstitial lung disease exacerbations and progression: a systematic review.

Authors:  Malik A Althobiani; Rebecca A Evans; Jaber S Alqahtani; Abdulelah M Aldhahir; Anne-Marie Russell; John R Hurst; Joanna C Porter
Journal:  ERJ Open Res       Date:  2021-12-20

8.  Pulmonary 18F-FDG uptake helps refine current risk stratification in idiopathic pulmonary fibrosis (IPF).

Authors:  Thida Win; Nicholas J Screaton; Joanna C Porter; Balaji Ganeshan; Toby M Maher; Francesco Fraioli; Raymondo Endozo; Robert I Shortman; Lynn Hurrell; Beverley F Holman; Kris Thielemans; Alaleh Rashidnasab; Brian F Hutton; Pauline T Lukey; Aiden Flynn; Peter J Ell; Ashley M Groves
Journal:  Eur J Nucl Med Mol Imaging       Date:  2018-01-16       Impact factor: 9.236

9.  Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice.

Authors:  Julia Duerr; Dominik H W Leitz; Magdalena Szczygiel; Dmytro Dvornikov; Simon G Fraumann; Clemens Kreutz; Piotr K Zadora; Ayça Seyhan Agircan; Philip Konietzke; Theresa A Engelmann; Jan Hegermann; Surafel Mulugeta; Hiroshi Kawabe; Lars Knudsen; Matthias Ochs; Daniela Rotin; Thomas Muley; Michael Kreuter; Felix J F Herth; Mark O Wielpütz; Michael F Beers; Ursula Klingmüller; Marcus A Mall
Journal:  Nat Commun       Date:  2020-04-24       Impact factor: 14.919

10.  Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule.

Authors:  Preethi Vijayaraj; Aspram Minasyan; Abdo Durra; Saravanan Karumbayaram; Mehrsa Mehrabi; Cody J Aros; Sarah D Ahadome; David W Shia; Katherine Chung; Jenna M Sandlin; Kelly F Darmawan; Kush V Bhatt; Chase C Manze; Manash K Paul; Dan C Wilkinson; Weihong Yan; Amander T Clark; Tammy M Rickabaugh; W Dean Wallace; Thomas G Graeber; Robert Damoiseaux; Brigitte N Gomperts
Journal:  Cell Rep       Date:  2019-12-10       Impact factor: 9.423
  10 in total

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