Na Guo1, Guojie Zhang2, Dawei Zhu3, Jian Wang4, Luwen Shi5. 1. School of Pharmaceutical Sciences, Peking University, No. 38 XueyuanLu Road, 100191 Beijing, China; International Research Center for Medicinal Administration, Peking University, No. 38 XueyuanLu Road, 100191 Beijing, China. Electronic address: guonasun@126.com. 2. Peking Union Medical College Hospital, No. 1 Shuaifuyuan, Wangfujing, Dongcheng District, 100730 Beijing, China. Electronic address: zhangguojie@pumch.cn. 3. Center for Health Policy and Management, Institute of Medical Information & Library, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 3 Yabao Road, Chaoyang District, 100020 Beijing, China. Electronic address: zhu_dawei@163.com. 4. School of Public Health, Shandong University, No. 44 Wenhuaxi Road, Lixia District, 265400 Jinan, China. Electronic address: wangjiannan@sdu.edu.cn. 5. School of Pharmaceutical Sciences, Peking University, No. 38 XueyuanLu Road, 100191 Beijing, China; International Research Center for Medicinal Administration, Peking University, No. 38 XueyuanLu Road, 100191 Beijing, China. Electronic address: shilu@bjmu.edu.cn.
Abstract
BACKGROUND: Vaccination is an effective way to prevent infectious diseases. Most studies analysed people's vaccine decisions, but few studies have analysed the effects of convenience such as immunisation schedule and distance and the quality of vaccination service on vaccination uptake. OBJECTIVE: The aim of this paper was to investigate adults' preferences for convenience and quality of vaccination service, calculate the private economic benefit from convenience (vaccination schedule and distance) and quality, and predict the uptake rate for different vaccine scenarios. METHODS: In our study, we interviewed 266 adults in 2 counties of Shandong province in China. The discrete choice experiment (DCE) was employed to analyse the preference for hepatitis B virus (HBV) vaccination, and a mixed logit model was used to estimate respondent preferences for vaccination attributes included in the DCE. RESULTS: The protection rate against hepatitis B (HB), duration of protection, risk of side effects, vaccination cost, schedule, and vaccination sites were proved to influence adults' preferences for HBV vaccination. The estimated willingness to pay (WTP) for 1 dose schedule instead of 3 doses and for a third-level vaccination site instead of a first-level site was almost equal (19 RMB). However, if the protection duration of the vaccination programme changed from 5years to 20years, the adults were willing to pay 35.05 RMB, and WTP for a 99% protection rate instead of a 79% rate was 67.71 RMB. The predicted uptake rate is almost 43% for the base case of HBV vaccination. CONCLUSIONS: Adults made trade-offs between vaccination schedules, vaccination sites, and other characteristics of HBV vaccine. The impact of attributes of the vaccine itself, especially protection rate against HB, duration of protection, and risk of side-effects, is more dramatic than convenience and quality of vaccination service.
BACKGROUND: Vaccination is an effective way to prevent infectious diseases. Most studies analysed people's vaccine decisions, but few studies have analysed the effects of convenience such as immunisation schedule and distance and the quality of vaccination service on vaccination uptake. OBJECTIVE: The aim of this paper was to investigate adults' preferences for convenience and quality of vaccination service, calculate the private economic benefit from convenience (vaccination schedule and distance) and quality, and predict the uptake rate for different vaccine scenarios. METHODS: In our study, we interviewed 266 adults in 2 counties of Shandong province in China. The discrete choice experiment (DCE) was employed to analyse the preference for hepatitis B virus (HBV) vaccination, and a mixed logit model was used to estimate respondent preferences for vaccination attributes included in the DCE. RESULTS: The protection rate against hepatitis B (HB), duration of protection, risk of side effects, vaccination cost, schedule, and vaccination sites were proved to influence adults' preferences for HBV vaccination. The estimated willingness to pay (WTP) for 1 dose schedule instead of 3 doses and for a third-level vaccination site instead of a first-level site was almost equal (19 RMB). However, if the protection duration of the vaccination programme changed from 5years to 20years, the adults were willing to pay 35.05 RMB, and WTP for a 99% protection rate instead of a 79% rate was 67.71 RMB. The predicted uptake rate is almost 43% for the base case of HBV vaccination. CONCLUSIONS: Adults made trade-offs between vaccination schedules, vaccination sites, and other characteristics of HBV vaccine. The impact of attributes of the vaccine itself, especially protection rate against HB, duration of protection, and risk of side-effects, is more dramatic than convenience and quality of vaccination service.
Authors: Zhuoying Huang; Abram L Wagner; Muzi Lin; Xiaodong Sun; Brian J Zikmund-Fisher; Matthew L Boulton; Jia Ren; Lisa A Prosser Journal: Hum Vaccin Immunother Date: 2020-01-24 Impact factor: 3.452
Authors: Anh Tuan Le Nguyen; Xuan Thanh Thi Le; Toan Thanh Thi Do; Cuong Tat Nguyen; Long Hoang Nguyen; Bach Xuan Tran; Huong Thi Le Journal: Biomed Res Int Date: 2019-02-21 Impact factor: 3.411
Authors: Sarah Kreps; Sandip Prasad; John S Brownstein; Yulin Hswen; Brian T Garibaldi; Baobao Zhang; Douglas L Kriner Journal: JAMA Netw Open Date: 2020-10-01