T A Stokes1,2, D Kuehn1,2,3, M Hood4,5, D M Biko4, A Pavey1,2, C Olsen6, C E Hunt1,2. 1. Department of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD, USA. 2. Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. 3. Department of Pediatrics, Brody School of Medicine, East Carolina University, Greenville, NC, USA. 4. Department of Radiology, Walter Reed National Military Medical Center, Bethesda, MD, USA. 5. Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. 6. Department of Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Abstract
OBJECTIVE: To correlate magnetic resonance imaging (MRI) of body fat in preterm infants at the time of hospital discharge with same-day anthropometric measures, and to assess the clinical utility of body mass index (BMI), waist circumference (WC), and WC/length ratio as indicators of visceral fat. STUDY DESIGN: MRI performed prior to NICU discharge in 25 infants born preterm at <32 weeks gestation. Total body fat and visceral fat were quantified using a commercial software program. The Pearson correlation coefficient (r, 95% C.I.) was used to describe strength of association between MRI fat and anthropometric measures. RESULTS: BMI and weight at discharge were strongly correlated with total body fat (r = 0.95 and 0.89 respectively; p < 0.001). Total body fat as a % of body weight was moderately correlated with weight (r = 0.53), WC (r = 0.52), and BMI (r = 0.47). Weight, BMI, and ponderal index all were found to correlate with total visceral fat (r = 0.65, 0.64, 0.55 respectively) but WC did not (r = 0.28). WC/length ratio was not correlated with any MRI fat measurements. CONCLUSIONS: BMI and weight at discharge both correlate with MRI fat measurements. Our findings do not support the usefulness of measuring WC or WC/length ratio in preterm infants at term-equivalent age.
OBJECTIVE: To correlate magnetic resonance imaging (MRI) of body fat in preterm infants at the time of hospital discharge with same-day anthropometric measures, and to assess the clinical utility of body mass index (BMI), waist circumference (WC), and WC/length ratio as indicators of visceral fat. STUDY DESIGN: MRI performed prior to NICU discharge in 25 infants born preterm at <32 weeks gestation. Total body fat and visceral fat were quantified using a commercial software program. The Pearson correlation coefficient (r, 95% C.I.) was used to describe strength of association between MRI fat and anthropometric measures. RESULTS: BMI and weight at discharge were strongly correlated with total body fat (r = 0.95 and 0.89 respectively; p < 0.001). Total body fat as a % of body weight was moderately correlated with weight (r = 0.53), WC (r = 0.52), and BMI (r = 0.47). Weight, BMI, and ponderal index all were found to correlate with total visceral fat (r = 0.65, 0.64, 0.55 respectively) but WC did not (r = 0.28). WC/length ratio was not correlated with any MRI fat measurements. CONCLUSIONS: BMI and weight at discharge both correlate with MRI fat measurements. Our findings do not support the usefulness of measuring WC or WC/length ratio in preterm infants at term-equivalent age.
Entities:
Keywords:
Anthropometric measures; body mass index; magnetic resonance imaging (MRI); prematurity
Authors: Kwang-Sig Lee; Ho Yeon Kim; Se Jin Lee; Sung Ok Kwon; Sunghun Na; Han Sung Hwang; Mi Hye Park; Ki Hoon Ahn Journal: BMC Pregnancy Childbirth Date: 2021-03-02 Impact factor: 3.007