Literature DB >> 28404736

The Link Between Adipose Tissue Renin-Angiotensin-Aldosterone System Signaling and Obesity-Associated Hypertension.

Monica T J Schütten1, Alfons J H M Houben1, Peter W de Leeuw1, Coen D A Stehouwer2.   

Abstract

Obese individuals frequently develop hypertension, which is for an important part attributable to renin-angiotensin-aldosterone system (RAAS) overactivity. This review summarizes preclinical and clinical evidence on the involvement of dysfunctional adipose tissue in RAAS activation and on the renal, central, and vascular mechanisms linking RAAS components to obesity-associated hypertension.
Copyright © 2017 Int. Union Physiol. Sci./Am. Physiol. Soc.

Entities:  

Mesh：

Year:  2017        PMID： 28404736     DOI： 10.1152/physiol.00037.2016

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  35 in total

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