Literature DB >> 28403647

Parathyroid Hormone-Related Peptide: A Novel Endocrine Cardioprotective "Conditioning Mimetic".

Tanuka Datta1, Karin Przyklenk2,3,4, Nabanita S Datta2,5.   

Abstract

An as-yet limited body of evidence suggests that calcium-regulating endocrine hormones-in particular, parathyroid hormone-related peptide (PTHrP)-may have unappreciated cardioprotective effects. The current review focuses on the concept that PTHrP may, via modulation of classic cardioprotective signaling pathways, provide a novel strategy to attenuate myocardial ischemia-reperfusion injury.

Entities:  

Keywords:  heart; ischemia; mitogen-activated protein kinase phosphatase 1; parathyroid hormone–related peptide; reperfusion

Mesh：

Substances：

Year:  2017        PMID： 28403647     DOI： 10.1177/1074248417702976

Source DB:  PubMed          Journal:  J Cardiovasc Pharmacol Ther        ISSN： 1074-2484            Impact factor:   2.457


  3 in total

1.  Parathyroid Hormone-Related Peptide and Its Analog, Abaloparatide, Attenuate Lethal Myocardial Ischemia-Reperfusion Injury.

Authors:  Joseph Wider; Vishnu V R Undyala; Beate Lanske; Nabanita S Datta; Karin Przyklenk
Journal:  J Clin Med       Date:  2022-04-19       Impact factor: 4.964

Review 2.  Can the calcium-regulating hormones counteract the detrimental impact of pro-inflammatory damage-associated molecular patterns in the development of heart failure?

Authors:  Satenik H Adamyan; Knarik R Harutyunyan; Hermine T Abrahamyan; Drastamat N Khudaverdyan; Souren Mkrtchian; Anna S Ter-Markosyan
Journal:  J Investig Med       Date:  2021-05-05       Impact factor: 2.895

3.  Cardiovascular Safety of Abaloparatide in Postmenopausal Women With Osteoporosis: Analysis From the ACTIVE Phase 3 Trial.

Authors:  Felicia Cosman; Linda R Peterson; Dwight A Towler; Bruce Mitlak; Yamei Wang; Steven R Cummings
Journal:  J Clin Endocrinol Metab       Date:  2020-11-01       Impact factor: 5.958
  3 in total

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