Literature DB >> 28402117

Development of a One-Pot Synthetic Method for Multifunctional Oxazole Derivatives Using Isocyanide Dichloride.

Takahiro Soeta1, Akihiro Matsumoto1, Yoko Sakata1, Yutaka Ukaji1.   

Abstract

A one-pot synthetic method was developed for multifunctional dihydrooxazole and oxazole derivatives. New reaction sequences were developed involving the formation of isocyanide dichloride, an aldol-type reaction with aldehydes, and a nucleophilic addition-elimination reaction, which efficiently afforded the dihydrooxazole and oxazole scaffolds.

Entities:  

Year:  2017        PMID： 28402117     DOI： 10.1021/acs.joc.7b00296

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  4 in total

1.  Mechanistic Pathways in Amide Activation: Flexible Synthesis of Oxazoles and Imidazoles.

Authors:  Giovanni Di Mauro; Boris Maryasin; Daniel Kaiser; Saad Shaaban; Leticia González; Nuno Maulide
Journal:  Org Lett       Date:  2017-07-13       Impact factor: 6.005

2.  Synthesis of 2,5-diaryloxazoles through rhodium-catalyzed annulation of triazoles and aldehydes.

Authors:  Jian Li; Shang-Rong Zhu; Yue Xu; Xue-Chen Lu; Zheng-Bing Wang; Li Liu; De-Feng Xu
Journal:  RSC Adv       Date:  2020-06-30       Impact factor: 4.036

3.  Retracted Article: Metal-free [2+2+1] cycloaddition polymerization of alkynes, nitriles, and oxygen atoms to functional polyoxazoles.

Authors:  Lichao Dong; Tian Lan; Yin Liang; Shifeng Guo; Hao Zhang
Journal:  RSC Adv       Date:  2020-06-25       Impact factor: 4.036

4.  Copper-catalyzed S-arylation of Furanose-Fused Oxazolidine-2-thiones.

Authors:  Vilija Kederienė; Jolanta Rousseau; Marie Schuler; Algirdas Šačkus; Arnaud Tatibouët
Journal:  Molecules       Date:  2022-08-30       Impact factor: 4.927
  4 in total

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