Literature DB >> 28401752

Water-Soluble Polythiophene for Two-Photon Excitation Fluorescence Imaging and Photodynamic Therapy of Cancer.

Minhuan Lan, Shaojing Zhao, Yusheng Xie, Junfang Zhao1, Liang Guo1, Guangle Niu1, Ying Li1, Hongyan Sun, Hongyan Zhang1, Weimin Liu1, Jinyuan Zhang, Pengfei Wang1,2, Wenjun Zhang.   

Abstract

Positively charged water-soluble polythiophene (PT0) that could self-assemble into nanoparticles in pure water solution was designed and synthesized. PT0 exhibited high photostabilities and pH stabilities, excellent biocompatibility, strong 1O2 generation capability, and large two-photon absorption cross sections. Moreover, we showed that the fluorescence of PT0 was unaffected by the interference of biomolecules and metal ions. As an example application, PT0 was demonstrated to be capable of simultaneous cell imaging and photodynamic therapy under either one-photon or two-photon excitation modes.

Entities:  

Keywords:  PDT; conjugated polymer; fluorescence imaging; two photon

Mesh:

Substances:

Year:  2017        PMID: 28401752     DOI: 10.1021/acsami.6b15537

Source DB:  PubMed          Journal:  ACS Appl Mater Interfaces        ISSN: 1944-8244            Impact factor:   9.229


  4 in total

Review 1.  Strategies to Improve Photodynamic Therapy Efficacy of Metal-Free Semiconducting Conjugated Polymers.

Authors:  Na Sun; Xue Wen; Song Zhang
Journal:  Int J Nanomedicine       Date:  2022-01-19

Review 2.  Recent Advances in Photodynamic Therapy for Deep-Seated Tumors with the Aid of Nanomedicine.

Authors:  Wei-Peng Li; Chia-Jui Yen; Bo-Sheng Wu; Tak-Wah Wong
Journal:  Biomedicines       Date:  2021-01-12

3.  Effects of Neutral, Anionic and Cationic Polymer Brushes Grafted from Poly(para-phenylene vinylene) and Poly(para-phenylene ethynylene) on the Polymer's Photoluminescent Properties.

Authors:  Thomas Kerr-Phillips; Mona Damavandi; Lisa I Pilkington; Kathryn A Whitehead; Jadranka Travas-Sejdic; David Barker
Journal:  Polymers (Basel)       Date:  2022-07-06       Impact factor: 4.967

Review 4.  Fluorescent Polymers Conspectus.

Authors:  Guillermo Ahumada; Magdalena Borkowska
Journal:  Polymers (Basel)       Date:  2022-03-11       Impact factor: 4.329

  4 in total

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