Literature DB >> 28401233

Recent progress in transition-metal-catalyzed enantioselective indole functionalizations.

Jing-Biao Chen1, Yi-Xia Jia.   

Abstract

Numerous efficient synthetic methods for enantioselective indole functionalizations have emerged in recent years. This review summarizes the major achievements in the transition-metal-catalyzed enantioselective indole functionalization reactions since 2010 and focuses on C-C bond formation processes, including alkylations, arylations, cycloaddition reactions, and other reactions. It intends to give a compendious overview of the significant progress achieved in this area.

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Year:  2017        PMID: 28401233     DOI: 10.1039/c7ob00413c

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  14 in total

1.  CuH-Catalyzed Enantioselective Alkylation of Indole Derivatives with Ligand-Controlled Regiodivergence.

Authors:  Yuxuan Ye; Seoung-Tae Kim; Jinhoon Jeong; Mu-Hyun Baik; Stephen L Buchwald
Journal:  J Am Chem Soc       Date:  2019-02-20       Impact factor: 15.419

2.  Myoglobin-Catalyzed C-H Functionalization of Unprotected Indoles.

Authors:  David A Vargas; Antonio Tinoco; Vikas Tyagi; Rudi Fasan
Journal:  Angew Chem Int Ed Engl       Date:  2018-07-06       Impact factor: 15.336

3.  Dual vicinal functionalisation of heterocycles via an interrupted Pummerer coupling/[3,3]-sigmatropic rearrangement cascade.

Authors:  Mindaugas Šiaučiulis; Selma Sapmaz; Alexander P Pulis; David J Procter
Journal:  Chem Sci       Date:  2017-11-17       Impact factor: 9.825

Review 4.  C4-H indole functionalisation: precedent and prospects.

Authors:  Jagadeesh Kalepu; Parthasarathy Gandeepan; Lutz Ackermann; Lukasz T Pilarski
Journal:  Chem Sci       Date:  2018-04-20       Impact factor: 9.825

5.  Highly selective Diels-Alder and Heck arylation reactions in a divergent synthesis of isoindolo- and pyrrolo-fused polycyclic indoles from 2-formylpyrrole.

Authors:  Carlos H Escalante; Eder I Martínez-Mora; Carlos Espinoza-Hicks; Alejandro A Camacho-Dávila; Fernando R Ramos-Morales; Francisco Delgado; Joaquín Tamariz
Journal:  Beilstein J Org Chem       Date:  2020-06-17       Impact factor: 2.883

6.  Chiral phosphoric acid catalyzed aminative dearomatization of α-naphthols/Michael addition sequence.

Authors:  Zi-Lei Xia; Chao Zheng; Ren-Qi Xu; Shu-Li You
Journal:  Nat Commun       Date:  2019-07-17       Impact factor: 14.919

7.  Stereodivergent assembly of tetrahydro-γ-carbolines via synergistic catalytic asymmetric cascade reaction.

Authors:  Shi-Ming Xu; Liang Wei; Chong Shen; Lu Xiao; Hai-Yan Tao; Chun-Jiang Wang
Journal:  Nat Commun       Date:  2019-12-05       Impact factor: 14.919

8.  Electrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives.

Authors:  Kun Liu; Wenxu Song; Yuqi Deng; Huiyue Yang; Chunlan Song; Takfaoui Abdelilah; Shengchun Wang; Hengjiang Cong; Shan Tang; Aiwen Lei
Journal:  Nat Commun       Date:  2020-01-07       Impact factor: 14.919

9.  Regiocontrol in the oxidative Heck reaction of indole by ligand-enabled switch of the regioselectivity-determining step.

Authors:  Yu-Jie Wang; Chen-Hui Yuan; De-Zhao Chu; Lei Jiao
Journal:  Chem Sci       Date:  2020-09-23       Impact factor: 9.825

10.  Nickel-catalyzed C-H alkylation of indoles with unactivated alkyl chlorides: evidence of a Ni(i)/Ni(iii) pathway.

Authors:  Dilip K Pandey; Shidheshwar B Ankade; Abad Ali; C P Vinod; Benudhar Punji
Journal:  Chem Sci       Date:  2019-08-19       Impact factor: 9.825

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