Literature DB >> 28401180

Uncovering a new cellular origin for acute myeloid leukemia with lineage plasticity.

Melinda Czeh1, Frank Rosenbauer1.   

Abstract

Although acute myeloid leukaemia (AML) is assumed to be driven by transformed haematopoietic stem and progenitor cells, we have described recently a new pathway leading to AML from T-cell progenitors. Furthermore, we could identify a subgroup of human AML with gene expression profile suggesting T-lymphoid origin and potentially novel treatment.

Entities:  

Keywords:  Leukemia; T-cell progenitors; lineage plasticity; myeloid differentiation

Year:  2016        PMID： 28401180      PMCID： PMC5383360          DOI： 10.1080/23723556.2016.1268241

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  6 in total

Review 1.  Acute myeloid leukemia stem cells and CD33-targeted immunotherapy.

Authors:  Roland B Walter; Frederick R Appelbaum; Elihu H Estey; Irwin D Bernstein
Journal:  Blood       Date:  2012-01-27       Impact factor: 22.113

2.  Mixed-phenotype acute leukemia: clinical and laboratory features and outcome in 100 patients defined according to the WHO 2008 classification.

Authors:  Estella Matutes; Winfried F Pickl; Mars Van't Veer; Ricardo Morilla; John Swansbury; Herbert Strobl; Andishe Attarbaschi; Georg Hopfinger; Sue Ashley; Marie Christine Bene; Anna Porwit; Alberto Orfao; Petr Lemez; Richard Schabath; Wolf-Dieter Ludwig
Journal:  Blood       Date:  2011-01-12       Impact factor: 22.113

3.  Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors.

Authors:  Pia Riemke; Melinda Czeh; Josephine Fischer; Carolin Walter; Saeed Ghani; Matthias Zepper; Konstantin Agelopoulos; Stephanie Lettermann; Marie L Gebhardt; Nancy Mah; Andre Weilemann; Michael Grau; Verena Gröning; Torsten Haferlach; Dido Lenze; Ruud Delwel; Marco Prinz; Miguel A Andrade-Navarro; Georg Lenz; Martin Dugas; Carsten Müller-Tidow; Frank Rosenbauer
Journal:  EMBO J       Date:  2016-08-29       Impact factor: 11.598

4.  Lineage switch in acute leukemia.

Authors:  S Stass; J Mirro; S Melvin; C H Pui; S B Murphy; D Williams
Journal:  Blood       Date:  1984-09       Impact factor: 22.113

5.  Lineage switching in acute leukemias: a consequence of stem cell plasticity?

Authors:  Elisa Dorantes-Acosta; Rosana Pelayo
Journal:  Bone Marrow Res       Date:  2012-07-19

Review 6.  Role of tyrosine-kinase inhibitors in myeloproliferative neoplasms: comparative lessons learned.

Authors:  Javier Pinilla-Ibarz; Kendra L Sweet; Gabriela M Corrales-Yepez; Rami S Komrokji
Journal:  Onco Targets Ther       Date:  2016-08-10       Impact factor: 4.147
  6 in total
  1 in total

Review 1.  Cancer Stem Cells-Origins and Biomarkers: Perspectives for Targeted Personalized Therapies.

Authors:  Lia Walcher; Ann-Kathrin Kistenmacher; Huizhen Suo; Reni Kitte; Sarah Dluczek; Alexander Strauß; André-René Blaudszun; Tetyana Yevsa; Stephan Fricke; Uta Kossatz-Boehlert
Journal:  Front Immunol       Date:  2020-08-07       Impact factor: 7.561
  1 in total

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