Flavour chemicals in a sample of non-cigarette tobacco products without explicit flavour names sold in New York City in 2015.

BACKGROUND: Youth who experiment with tobacco often start with flavoured products. In New York City (NYC), local law restricts sales of all tobacco products with 'characterising flavours' except for 'tobacco, menthol, mint and wintergreen'. Enforcement is based on packaging: explicit use of a flavour name (eg, 'strawberry') or image depicting a flavour (eg, a fruit) is presumptive evidence that a product is flavoured and therefore prohibited. However, a tobacco product may contain significant levels of added flavour chemicals even when the label does not explicitly use a flavour name.
METHODS: Sixteen tobacco products were purchased within NYC in 2015 that did not have explicit flavour names, along with three with flavour names. These were analysed for 92 known flavour chemicals plus triacetin by gas chromatography/mass spectrometry.
RESULTS: 14 of the 16 products had total determined flavour chemical levels that were higher (>0.3 mg/g) than in previously studied flavour-labelled products and of a chemical profile indicating added flavour chemicals.
CONCLUSIONS: The results suggest that the tobacco industry has responded to sales restrictions by renaming flavoured products to avoid explicitly identifying them as flavoured. While chemical analysis is the most precise means of identifying flavours in tobacco products, federal tobacco laws pre-empt localities from basing regulations on that approach, limiting enforcement options. If the Food and Drug Administration would mandate that all tobacco products must indicate when flavourings are present above a specific level, local jurisdictions could enforce their sales restrictions. A level of 0.1 mg/g for total added flavour chemicals is suggested here as a relevant reference value for regulating added flavour chemicals in tobacco products. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Introduction

It is widely recognised that flavoured tobacco products appeal to youth and that youth who experiment with tobacco often start with flavoured products.1 Tobacco control professionals have therefore identified restrictions on flavoured tobacco products as a policy goal that has potential to reduce youth tobacco use.2 Given the importance of reducing the number of children who start to smoke and become addicted to dangerous tobacco products, in September 2009, Congress prohibited flavoured cigarette production, except for menthol, as part of the Family Smoking Prevention and Tobacco Control Act (FSPTCA).3 4 Notably, the federal law says a cigarette ‘shall not contain, as a constituent…or additive, an artificial or natural flavor…. that is a characterizing flavor of the tobacco product or tobacco smoke’. Note that low levels of flavour additives that do not yield a ‘characterising flavour’ are neither banned nor more explicitly defined. The FSPTCA does authorise the Food and Drug Administration (FDA) to mandate disclosures to the FDA on constituents, ingredients and additives, which could be used to require disclosures of flavourings for all regulated tobacco products. Currently, the content of those disclosures is not released to the public or local jurisdictions that regulate tobacco products. In a recent editorial in this journal on flavoured tobacco products in the USA, Stanton et al 5 conclude that ‘further data across disciplines with rigorous methods are needed to inform policy decisions regarding the regulation of flavours in tobacco products that can reduce initiation of tobacco products, promote cessation of tobacco products among users and ultimately reduce exposure to harmful products to protect population health’.

In October 2009, to extend the protection conferred by the FSPTCA, New York City (NYC) restricted retail sales of tobacco products other than cigarettes (ie, ‘OTP’) having ‘characterising flavours’ other than ‘tobacco, menthol, mint or wintergreen’ as summarised in Box 1.6 7 Electronic cigarette products are not addressed by this law. ‘Tobacco bars’, a narrow class of food service establishments that have been required to register annually with NYC since 2002 (and currently numbering eight), are not subject to the flavoured tobacco regulation. Consistent with the FSPTCA, the NYC ordinance defined ‘flavored’ as ‘contains a constituent that imparts a characterizing flavor’.7 The ordinance further states that a ‘public statement or claim made or disseminated by the manufacturer of a tobacco product…that such tobacco product has or produces a characterizing flavor shall constitute presumptive evidence that the tobacco product is a flavored tobacco product'. As a result of this provision, tobacco product packaging labelled with the name of a flavour, or a picture connoting that flavour—such as ‘strawberry', or a picture of a strawberry, constitutes presumptive evidence that sale of the product is illegal in NYC. Several other local jurisdictions have enacted laws restricting the sale of flavoured OTP; these include Providence, Rhode Island; Minneapolis, Minnesota; Chicago, Illinois; Boston, Massachusetts, and various smaller Massachusetts towns. Most of these localities, like NYC, rely on product names as the primary means of identifying flavoured products.

New York City ordinance approved 14 October 2009:6 ‘A local law to amend the New York City charter and the administrative code of the city of New York, in relation to the regulation of tobacco products: Int 0433–2006’. (Upheld in Federal Court: US Smokeless Tobacco Manufacturing Company LLC et al v. City Of New York, Docket No. 11–5167-cv. Decided 26 February 2013 in the United States Court of Appeals, Second Circuit).

Definitions in the ordinance

‘Flavored tobacco product’ means any tobacco product or any component part thereof that contains a constituent that imparts a characterizing flavor.

‘Characterizing flavor’ means a distinguishable taste or aroma, other than the taste or aroma of tobacco, menthol, mint or wintergreen, imparted either prior to or during consumption of a tobacco product or component part thereof, including, but not limited to, tastes or aromas relating to any fruit, chocolate, vanilla, honey, candy, cocoa, dessert, alcoholic beverage, herb or spice, provided; however, that no tobacco product shall be determined to have a characterizing flavor solely because of the use of additives or flavorings or the provision of ingredient information.

Banned in the ordinance

§17–715 Sale of flavored tobacco products prohibited. It shall be unlawful for any person to sell or offer for sale any flavored tobacco product except in a tobacco bar.

Enforcement of the NYC law began in November 2010, and citations for violations have been based on use of explicit flavour names and/or images on the packages. Some NYC retailers, however, are now selling colourfully packaged tobacco products that, although not carrying explicit flavour indicators, smell distinctly of flavour variations other than tobacco, menthol, mint or wintergreen. Although cigarillos labelled ‘Blueberry’ and ‘Strawberry’ have largely disappeared from store shelves, noticeably flavoured ‘Blue’ and ‘Pink’ cigarillos are increasingly common in NYC. Cigarillos under the brand name Show, labelled ‘Ba Boom’, are sold in green/black/orange packages. Bluntville branded ‘Piff’ cigarillos are sold in purple packages, ‘blunt’ and ‘piff’ having cannabis connotations. Although NYC rules pertaining to the flavour prohibition allow for sensory testing to identify flavoured products, this enforcement mechanism has not been used to date. Nationally, Viola et al 8 note that ‘the cigar industry may be pre-emptively steering away from overt flavour descriptors, instead relying on more generic names on their packaging in anticipation of a [federal] ban on flavoured cigars’. Manufacturers may also be anticipating a proliferation of local sales restrictions on flavoured products, taking advantage of the commercial convenience of selecting names that can be used in any jurisdiction. Also, it cannot be excluded that some manufacturers may simply believe that there is consumer demand for products with colourful or catchy names that do not explicitly reference flavours, though for cigarettes, Lempert and Glantz9 present arguments that tobacco companies do use colour on packaging and labelling as a replacement for now-prohibited descriptive words such as ‘light’ and ‘mild’.

During a media-briefing conference call on 5 May 2016,10 and in regulations published on 10 May, 2016,11 the FDA stated that it anticipates issuing a proposed rule that extends its ban on flavoured cigarettes to also prohibit flavoured cigars. It is reasonable to consider that the proposed rule might track the language that prohibits flavoured cigarettes, saying a cigar ‘shall not carry a characterizing flavor’, as well as requiring cigar manufacturers to disclose product constituents/additives information to the FDA. However, Viola et al 8 nevertheless caution that: ‘An appropriate definition for ‘characterising flavours’ that takes into account product ingredients may be necessary to fully capture cigar products that are distinctly flavoured’.

Here we describe the results of a study in which 19 tobacco products purchased in NYC were subjected to chemical analyses to determine the extent to which common non-cigarette tobacco products not labelled as containing flavours contain flavour chemicals. The levels found are compared both within the group, and relative to levels previously measured by Brown et al 12 for tobacco products carrying explicit flavour names.

Methods

A convenience sample of 16 non-cigarette tobacco products without explicit flavour names were purchased within NYC in February and March 2015 (table 1 a, b). Three additional products with flavour names were purchased: (1) Skoal ‘Citrus’ moist snuff; (2) Black and Mild ‘Cream’ ‘pipe-tobacco cigars’ and (3) Camel ‘Frost’ Snus. The law explicitly applies to tobacco products with ‘tastes or aromas relating to any fruit [or] … dessert’.7 Because ‘citrus’ is associated with fruits, and cream is associated with desserts, and a product’s name is a ‘public statement or claim’ suggesting the product is flavoured, the first two products are covered by the law as presumptively flavoured tobacco products.13 The ‘frost’ product is not presumptively prohibited under the NYC regulations as it is not distinctly a dessert, fruit, herb or spice name, and even if it were argued to be a unique characterising flavour, a counterargument could be made that it is more akin to products that fall under the menthol exception than presumptively flavoured tobacco products.

Photographic images of the 19 packages of tobacco product samples were recorded (see online supplementary figures S1 to S5). Each of the 19 products was analysed in triplicate. For each analysis, approximately 1.0 g was weighed into a 40 mL glass phial, then spiked with 50 µL of a surrogate standard (SS) solution of 1,3,5-triclorobenzene in methanol at 4880 ng/µL. For cigars and cigarillos, each 1.0 g sample was cut from the centre of a complete rod, and so included the wrap and the filler. For snus and snuff products, 1.0 g of the loose product was used. For products of the pouch type, one pouch was extracted. Ten millilitres of high-purity methanol was then added to the phial. After extraction for 2 hours (with shaking), each phial was allowed to sit for 10 hours to allow separation of the methanol solution from the tobacco material. One millilitre of the extract was placed in a 2 mL autosampler phial and spiked with 20 µL of an internal standard (IS) solution of 1,2,3-trichlorobenzene at 1000 ng/µL in methanol. Each IS-spiked extract was analysed by gas chromatography/mass spectrometry (GC/MS) using an Agilent (Santa Clara, California, USA) 7693 autosampler, Agilent 7890A GC and Agilent 5975 C MS. The GC column type was Restek (Bellefonte, Pennsylvania, USA) Rxi-5Sil MS, of 30 m length, 0.25 mm i.d. and 0.25 mm film thickness. For each sample, 1.0 µL was injected with a 15:1 split. The GC temperature programme for all analyses was: 35°C hold for 5 min; 10°C/min to 300°C, then hold for 3.5 min at 300°C. The MS source temperature was 250°C. The MS was operated in the electron impact ionisation mode with an ionisation potential of 70 eV, with scanning from 34 to 400 atomic mass units.

The analyses were carried out using authentic standards for 93 compounds comprising the target analyte list. This list included diacetyl (2,3-buanedione), acetyl propionyl (2,3-pentanedione) and triacetin, plus the 90 compounds selected by Tierney et al 14 based on analyses of a range of electronic cigarette fluids. As usual for analyses by GC/MS: (1) the confirmed presence of a given analyte in a particular sample required a match between the sample run and a standard for both: (a) the GC retention time and (b) the MS fragmentation pattern; and (2) quantitation proceeded by comparison with calibration standard runs. Values >1 µg/g (0.001 mg/g) are reported here.

Results

The calculated SS extraction recoveries ranged from 85.7% to 108.1%; the average recovery ±1 SD was 96.4%±5.0%. For the sample of each product, the coefficient of variation (CV) was calculated for the triplicate process subsampling the product, extracting with solvent, then conducting analysis by GC/MS. The mean CV ±1 SD was 5.4%±3.3% for determinations larger than 1000 µg/g, 5.2%±3.0% for determinations between 100 and 1000 µg/g and 9.9%±7.1% for determinations lower than 100 µg/g. Sixty-three of the 93 target compounds were detected in the 19 samples at levels ranging from 1 µg/g to 11 000 µg/g.

The results are summarised in table 1 a, b, online supplementary tables S1.a and S1.b and figure 1. Of the 16 products without explicit flavour names, the two with the lowest total determined flavour chemicals levels were Camel brand ‘Robust’ snus (#15) at 271 µg/g (0.271 mg/g) and Peach brand ‘Sweet Snuff’ (#16) at 65 µg/g (0.065 mg/g). The differences in the flavour profiles of these two products versus those of products #1 to #16 can be surmised based on table 1 a, b. The common peach flavour compounds γ-decalactone and γ-undecalactone were not found in Peach brand ‘Sweet Snuff’ (#16). Therefore, absent additional information, manufacturing of at least the latter may not have involved addition of flavour chemicals of the type considered here. However, for Zig Zag ‘Pink’ cigars (#14), the total determined flavour chemical level was 941 µg/g (0.941 mg/g), with vanillin at 698 µg/g (0.698 mg/g). It is certain that the Zig Zag ‘pink’ cigars (#14) were intentionally flavoured given that natural levels of vanillin in a range of types of tobacco leaf have been reported to be in the range 0.9–1.8 µg/g.15 The product with the highest level of total flavour chemicals was Show ‘Poco Loco’ cigarillos (#1) at 12 500 µg/g (12.5 mg/g).

Figure 1

Results for 16 products without explicit flavour names in bar plot form; the values for three products with flavour names examined in this study (A, B and C) are included for comparison. Additional values for reference are for products with explicit flavour names as derived from Brown et al 12 (see also table 1b). NYC, New York City.

Table 1b

Levels of flavour compounds (compounds 1–22) in six tobacco products (numbers 11–16) without explicit flavour names, and three tobacco products (A, B and C) with explicit flavour names, all purchased in February and March of 2015 in New York City. Products ranked (decreasing order) by totals for 93 chemicals determined. Values given are means for triplicate analyses. All values in micrograms (µg) of flavour chemical per gram of product (µg/(g of product)), using a maximum of three significant figures. Only values found to be >1.0 µg/g are given

		11	12	13	14	15	16	A	B	C
	Compound	Camel ‘Mellow’ snus(µg/g)	Hype ‘Blue Mixx’ cigarillos(µg/g)	D’Ville ‘Pink’ cigars(µg/g)	Zig Zag ‘Pink’ cigars(µg/g)	Camel ‘Robust’ snus(µg/g)	Peach ‘Sweet’ Snuff’(µg/g)	Skoal ‘Citrus’ moist snuff(µg/g)	Black & Mild ‘Cream’ ‘cigars’(µg/g)	Camel Snus ‘Frost’ moist snuff(µg/g)
	Total:	1830.	1600.	1120.	941.	271.	65.4	18 100.	15 000.	9300.
1	Ethyl vanillin	1470	10.0	599	25.3			451	11 000
2	Vanillin	11.3	698	413	698		8.37	644	3380	582
3	Benzyl alcohol	3.4	16.5	7.9	28.1	121		2980	6.08	5.4
4	Limonene	10.7			13.4	12.0		9510		108
5	Menthol				17.4	44.1		128		4290
6	Carvone							48.0		4070
7	Ethyl maltol			36.4	2.1			7.6	7.1
8	Methyl anthranilate		2.6	30.8	4.9
9	Linalool		264					900		5.2
10	Piperonal		86.0	6.1	4.3			17.1	227
11	Ethyl isovalerate							13.4
12	Z-3-hexen-1-ol		54.6		4.7			31.0
13	p-Anisaldehyde		10.1		7.2
14	Methyl salicylate	3.3				3.4		915		5.17
15	γ-Undecalactone				47.8			56.6
16	γ-Decalactone	94.2	38.6	5.3				70.9
17	Furfuryl alcohol		30.7				29.6		257
18	Raspberry ketone		59.4		13.7			161.0
19	Ethyl hexanoate							13.5
20	Maltol	13.3	218	13.8		10.6	10.8	9.4	102	16.7
21	α-Terpineol							582		26.1
22	Benzaldehyde propylene glycol acetal		34.4		8.9			174

The results for products 1 to 16 (ie, those without explicit flavour names) are plotted in figure 1; the values for the three products (A, B and C) with flavour names are included for reference, along with values derived from Brown, et al 12 for analyses (also by extraction then GC/MS) of multiple tobacco products with explicit flavour names (see table 2).

Table 2

Values derived from Brown et al 12 for products with explicit flavour names, recomputed from amount ‘per serving’ to µg per g tobacco product

Product	Total flavour concentration (µg/g)
Skoal ‘Cherry’ moist snuff	12 600
Skoal ‘Berry Blend’ moist snuff	11 200
Zig Zag Wraps ‘Cherry’ blunt wraps	6840
Kayak ‘Apple’ moist snuff	5300
Zig Zag Wraps ‘Grape’ blunt wraps	5300
Cheyenne ‘Wild Cherry’ " large cigars’	5130
Kayak ‘Grape’ moist snuff	5080
Phillies Blunt ‘Grape’ cigar	4560
Zig Zag Wraps ‘Apple’ blunt wraps	4430
Kayak ‘Peach’ moist snuff	3720
Cheyenne ‘Grape’ " large cigars’	3480
Zig Zag Wraps ‘Blueberry’ blunt wraps	3450
Skoal ‘Apple’ moist snuff	2790
Cheyenne ‘Xotic Berry’ ‘large cigars’	2630
Swisher Sweet ‘BLK Cherry’ cigarillos	2340
Swisher Sweet ‘Peach’ cigarillos	1010
Cheyenne ‘Peach’ ‘large cigars’	571
Royal Blunt XXL ‘Sour Apple’ blunt wraps	313

Discussion

Tobacco products without explicit flavour names that have been available for purchase in NYC are, in fact, flavoured. Fourteen out of 16 products without explicit flavour names were found to contain total flavour chemical levels higher than the lowest level product with an explicit flavour name examined previously12 (Royal XXL ‘Sour Apple’ blunt wraps, 0.313 mg/g; table 2). The results suggest that the tobacco industry may have anticipated or responded to restrictions on the sale of flavoured products by introducing flavoured products without characterising flavour names, using packaging to imply that certain products are flavoured.

As noted above, in May 2016, the FDA exercised its authority to expand the range of tobacco products subject to its regulatory authority by deeming the definition of tobacco products to include cigars, tobacco-containing shisha smoked in hookah pipes, pipe tobacco, e-cigarettes and liquid e-cigarette refills and more.11 The FDA will thereby require manufacturers of these products to report on constituents, ingredients and additives. The FDA also announced that it plans to issue proposed rules that would extend its ban on ‘characterising flavours’ for cigarettes to cover cigars. Presumably, such a ban could not be sidestepped simply by removing flavour names from packages. Even with a federal prohibition on the production of flavoured cigars, other flavoured tobacco would still be marketed and sold (smokeless tobacco, pipe tobacco and shisha). For those products, local jurisdictions such as NYC with restrictions on the sale of flavoured products would still confront the challenge of identifying flavoured tobacco products when the label does not explicitly reference a flavour (local jurisdictions are pre-empted from regulating tobacco manufacturing processes and cannot address product ingredients directly).

The FDA deeming rules subject OTPs to federal regulations, including reporting requirements on constituents, ingredients and additives. However, local jurisdictions are not privy to such information. As a result, localities may still be reliant on labelling information to identify flavoured products which, as this paper demonstrates, may be an underinclusive approach. If the FDA were to require manufacturers to label tobacco products as ‘flavoured’ when they have greater than a specific maximum permissible added level of certain ingredients, local jurisdictions would be able to enforce sales restrictions more effectively.

Because the products examined here were obtained as a convenience sample, all study-relevant tobacco products available in NYC in 2015 were not analysed. Nevertheless, the results indicate that the samples ranged from some that were clearly overtly flavoured to others that had low overall flavour levels, and so the study-relevant range of flavour levels has probably been correctly identified. Second, the number of flavour-related target analyte chemicals was capped at 93. Nevertheless, although some added flavour compounds present in the samples may have thus escaped being reported on this work, as noted above, none of these contributed in a major way to any given sample.

The establishment of any particular regulatory level for total added flavour chemicals vis a vis the term ‘characterizing flavour’ is notably complicated by variable sensitivity among the population in detecting flavour chemicals (eg, see Deems16), compound-by-compound variability in odour potency, compound-by-compound inherent variability in volatility, which is required for odour detection, and dependence of flavour compound volatility on product type (eg, products of different water contents). Nevertheless, we propose that some specific level for total added flavour chemicals be considered as the demarcation for ‘characterizing flavour’. A level such as 0.1 mg/g or lower might be considered. It is: (1) ~1/3 the 0.313 mg/g value for total determined flavour chemicals found by Brown et al 12 to have been used in the admittedly ‘apple’-flavoured Royal Blunt XXL ‘Sour Apple’ blunt wraps (see tables 1 a, b); and (2) of the same magnitude found here for Peach brand (but not peach flavoured) ‘Sweet Snuff’ (0.065 mg/g). Some will object to a suggested level of 0.1 mg/g, given the large range of flavour chemicals used in foods and beverages (see Burdock17). Moreover, distinguishability by smell relative to tobaccos without any added flavour chemicals will be likely possible for some of the chemicals at values lower than 0.1 mg/g. However, given that portions of the US tobacco industry readily acknowledge use of chemicals as flavour additives (including in cigarettes),18 many (if not most) tobacco products are already distinguishable by smell from unflavoured tobacco. Consequently, stricter regulations on levels of total added flavour chemicals may not require or be enhanced by the continued use of the term ‘characterizing flavour’. Last, revisions to regulatory levels are always possible and have been implemented numerous times for ambient atmospheric pollutants: for example, the regulatory value for the 8-hour average for ozone in the USA was set at 0.080 ppb in 1997, 0.075 ppb in 2008 and 0.070 ppb in 2015 (all values are parts per billion (ppb) by volume in air).19

New York City (NYC) currently prohibits sales of tobacco products having ‘characterising flavours’ other than ‘tobacco, menthol, mint or wintergreen', except as may occur in ‘tobacco bars'. Enforcement action may take place when products are explicitly labelled with a recognisable flavour name (eg, cherry and vanilla) or flavour image (eg, fruit and candy). Chemical testing of products cannot be used as a basis for enforcement by a state or local jurisdiction because federal law pre-empts local regulations based on tobacco product standards (eg, a city or state likely cannot ban specific flavourings based on chemical analyses).

A convenience sample of 19 tobacco products were purchased in NYC in 2015. Sixteen tobacco products did not have explicit flavour names. All products were analysed by gas chromatography/mass spectrometry. Fourteen tobacco products were found to contain total determined flavour chemical levels higher than the lowest total level (0.313 mg/g) found in 18 tobacco products with flavour names previously analysed by our laboratory.

The results indicate that most (if not all) of the 14 have a ’characterising flavour', likely constituting a violation of the NYC ordinance: manufacturers may be responding to local adoption of laws restricting the sale of flavoured products by avoiding explicit flavour names.

The Food and Drug Administration (FDA) has announced a plan to prohibit flavoured cigars. Such a step would advance local efforts to reduce availability of flavoured ‘other tobacco products’ (OTPs), although localities that restrict the sale of flavoured OTPs would still contend with enforcement challenges related to flavoured smokeless tobacco, pipe tobacco and tobacco-containing shisha.

This work suggests that the FDA could consider using its unique power to regulate ingredients and flavourings to help local jurisdictions enforce their restrictions on the sale of flavoured tobacco products. For example, the FDA could decide to require all tobacco products with more than some particular total number of milligrams of total flavour chemicals per gram of product to bear a disclosure on their label stating ‘This is a flavoured tobacco product’.

Table 1a

Levels of flavour-related chemicals (compounds 1–22) in 10 tobacco products (1–10) without explicit flavour names purchased in February and March of 2015 in New York City. Products ranked (decreasing order) by totals for 93 chemicals determined. Values given are means for triplicate analyses. All values in micrograms (µg) of flavour chemical per gram of product (µg/(g of product)), using a maximum of three significant figures. Only values found to be >1.0 µg/g are given

			1	2	3	4	5	6	7	8	9	10
	Compound	Average for all 19 products(µg/g)	Show ‘Poco Loco’ cigarillos(µg/g)	Show ‘TaTa’ cigarillos(µg/g)	Bluntville ‘Piff’ cigarillos(µg/g)	Show ‘Ba Boom’ cigarillos(µg/g)	Black & Mild ‘Royale’ cigars(µg/g)	Hype ‘Sweet’ cigarillos(µg/g)	Show ‘Buzz’ cigarillos(µg/g)	Bluntville ‘Blue’ cigarillos(µg/g)	Rock n’ Roll ‘Blue’ cigars(µg/g)	Hype ‘Purple Reserve’ cigarillos(µg/g)
	Total:	5460.	12 500.	7880.	7810.	5440.	4480.	4440.	4170.	3460.	3420.	1930.
1	Ethyl vanillin	1380	1830	1500	2170	13.5	535	2070	1640	577	1860	383
2	Vanillin	899	1110	1060	1340	1270	1050	840	438	1670	1490	385
3	Benzyl alcohol	810	494	2580	1310	1630	5.8	1000	133	288	4.08	324
4	Limonene	623	1330	643		192			20.1
5	Menthol	236
6	Carvone	217
7	Ethyl maltol	208	517	392	127	1020	686		986		33.8	149
8	Methyl anthranilate	157		2.2	2780	13.7			1.8	17.7		125
9	Linalool	136	658	363				2.8	22.5	372		3.33
10	Piperonal	75.4	59.1	33.4	29.0		713	2.6	108	99.0		48.6
11	Ethyl isovalerate	60.9	485	331		30.8			297
12	Z-3-hexen-1-ol	59.0	189	169		589.				82.5
13	p-Anisaldehyde	52.2	160	85.0	9.4	6.8		483		4.40		225
14	Methyl salicylate	48.8
15	γ-Undecalactone	46.5	4.0	1.30			774
16	γ-Decalactone	43.7	235	128		192				65.2
17	Furfuryl alcohol	37.4					274	14.8	26.1		12.9	64.9
18	Raspberry ketone	37.0	46.2	53.2			110		152	60.1		46.8
19	Ethyl hexanoate	36.5	259	154					268.
20	Maltol	36.4	19.2	12.4	11.6		80.5	6.1		156	5.8	5.5
21	α-Terpineol	35.9	43.6	22.4					8.1
22	Benzaldehyde propylene glycol acetal	30.4	97.5	100	2.3	2.7	11.4	2.7	5.1	30.0	1.9	106