| Literature DB >> 2839998 |
E Hollander1, M Fay, B Cohen, R Campeas, J M Gorman, M R Liebowitz.
Abstract
Six of eight patients with obsessive-compulsive disorder had an exacerbation of symptoms when given m-chlorophenylpiperazine. Fenfluramine and placebo produced mild improvement. Six patients given intravenous clonidine experienced marked reduction in obsessions. Implications for serotonergic and noradrenergic hypotheses of obsessive-compulsive disorder are discussed.Entities:
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Year: 1988 PMID: 2839998 DOI: 10.1176/ajp.145.8.1015
Source DB: PubMed Journal: Am J Psychiatry ISSN: 0002-953X Impact factor: 18.112