Literature DB >> 28399685

Pico145 - powerful new tool for TRPC1/4/5 channels.

Hussein N Rubaiy1, Melanie J Ludlow1, Robin S Bon1, David J Beech1.   

Abstract

Entities:  

Keywords:  Transient Receptor Potential; anxiety; calcium ion; cardiac remodelling; englerin; epilepsy; non-selective cationic channel; pain; pharmacology; sodium ion

Mesh：

Substances：

Year:  2017        PMID： 28399685      PMCID： PMC5626370          DOI： 10.1080/19336950.2017.1317485

Source DB:  PubMed          Journal:  Channels (Austin)        ISSN： 1933-6950            Impact factor:   2.581


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  8 in total

Review 1.  TRPs in our senses.

Authors:  Nils Damann; Thomas Voets; Bernd Nilius
Journal:  Curr Biol       Date:  2008-09-23       Impact factor: 10.834

Review 2.  Characteristics of transient receptor potential canonical calcium-permeable channels and their relevance to vascular physiology and disease.

Authors:  David J Beech
Journal:  Circ J       Date:  2013-02-14       Impact factor: 2.993

Review 3.  In pursuit of small molecule chemistry for calcium-permeable non-selective TRPC channels -- mirage or pot of gold?

Authors:  Robin S Bon; David J Beech
Journal:  Br J Pharmacol       Date:  2013-10       Impact factor: 8.739

Review 4.  Physiology and pathophysiology of canonical transient receptor potential channels.

Authors:  Joel Abramowitz; Lutz Birnbaumer
Journal:  FASEB J       Date:  2008-10-21       Impact factor: 5.191

5.  (-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels.

Authors:  Yasemin Akbulut; Hannah J Gaunt; Katsuhiko Muraki; Melanie J Ludlow; Mohamed S Amer; Alexander Bruns; Naveen S Vasudev; Lea Radtke; Matthieu Willot; Sven Hahn; Tobias Seitz; Slava Ziegler; Mathias Christmann; David J Beech; Herbert Waldmann
Journal:  Angew Chem Int Ed Engl       Date:  2015-02-23       Impact factor: 15.336

6.  Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.

Authors:  Hussein N Rubaiy; Melanie J Ludlow; Matthias Henrot; Hannah J Gaunt; Katarina Miteva; Sin Ying Cheung; Yasuyuki Tanahashi; Nurasyikin Hamzah; Katie E Musialowski; Nicola M Blythe; Hollie L Appleby; Marc A Bailey; Lynn McKeown; Roger Taylor; Richard Foster; Herbert Waldmann; Peter Nussbaumer; Mathias Christmann; Robin S Bon; Katsuhiko Muraki; David J Beech
Journal:  J Biol Chem       Date:  2017-03-21       Impact factor: 5.157

7.  (-)-Englerin A-evoked Cytotoxicity Is Mediated by Na+ Influx and Counteracted by Na+/K+-ATPase.

Authors:  Melanie J Ludlow; Hannah J Gaunt; Hussein N Rubaiy; Katie E Musialowski; Nicola M Blythe; Naveen S Vasudev; Katsuhiko Muraki; David J Beech
Journal:  J Biol Chem       Date:  2016-11-14       Impact factor: 5.157

Review 8.  Transient receptor potential canonical 4 and 5 proteins as targets in cancer therapeutics.

Authors:  Hannah J Gaunt; Naveen S Vasudev; David J Beech
Journal:  Eur Biophys J       Date:  2016-06-11       Impact factor: 1.733
  8 in total
  15 in total

Review 1.  Treasure troves of pharmacological tools to study transient receptor potential canonical 1/4/5 channels.

Authors:  Hussein N Rubaiy
Journal:  Br J Pharmacol       Date:  2019-03-06       Impact factor: 8.739

2.  Identification of an (-)-englerin A analogue, which antagonizes (-)-englerin A at TRPC1/4/5 channels.

Authors:  Hussein N Rubaiy; Tobias Seitz; Sven Hahn; Axel Choidas; Peter Habenberger; Bert Klebl; Klaus Dinkel; Peter Nussbaumer; Herbert Waldmann; Mathias Christmann; David J Beech
Journal:  Br J Pharmacol       Date:  2018-01-25       Impact factor: 8.739

3.  Tonantzitlolone is a nanomolar potency activator of transient receptor potential canonical 1/4/5 channels.

Authors:  Hussein N Rubaiy; Melanie J Ludlow; Karsten Siems; Katherine Norman; Richard Foster; Dietmar Wolf; John A Beutler; David J Beech
Journal:  Br J Pharmacol       Date:  2018-06-28       Impact factor: 8.739

4.  Bridgehead Modifications of Englerin A Reduce TRPC4 Activity and Intravenous Toxicity but not Cell Growth Inhibition.

Authors:  Zhenhua Wu; Jean-Simon Suppo; Sarka Tumova; Jonathan Strope; Fernando Bravo; Melody Moy; Ethan S Weinstein; Cody J Peer; William D Figg; William J Chain; Antonio M Echavarren; David J Beech; John A Beutler
Journal:  ACS Med Chem Lett       Date:  2020-08-03       Impact factor: 4.345

Review 5.  Canonical transient receptor potential channels and their modulators: biology, pharmacology and therapeutic potentials.

Authors:  Yuan-Yuan Gao; Wen Tian; Hui-Nan Zhang; Yang Sun; Jing-Ru Meng; Wei Cao; Xiao-Qiang Li
Journal:  Arch Pharm Res       Date:  2021-03-24       Impact factor: 4.946

Review 6.  Endothelial Ca2+ Signaling and the Resistance to Anticancer Treatments: Partners in Crime.

Authors:  Francesco Moccia
Journal:  Int J Mol Sci       Date:  2018-01-11       Impact factor: 5.923

Review 7.  Regulation of Vessel Permeability by TRP Channels.

Authors:  Tullio Genova; Deborah Gaglioti; Luca Munaron
Journal:  Front Physiol       Date:  2020-05-05       Impact factor: 4.566

8.  (-)-Englerin-A Has Analgesic and Anti-Inflammatory Effects Independent of TRPC4 and 5.

Authors:  João de Sousa Valente; Khadija M Alawi; Sabah Bharde; Ali A Zarban; Xenia Kodji; Dibesh Thapa; Fulye Argunhan; Brentton Barrett; Istvan Nagy; Susan D Brain
Journal:  Int J Mol Sci       Date:  2021-06-15       Impact factor: 5.923

Review 9.  Remarkable Progress with Small-Molecule Modulation of TRPC1/4/5 Channels: Implications for Understanding the Channels in Health and Disease.

Authors:  Aisling Minard; Claudia C Bauer; David J Wright; Hussein N Rubaiy; Katsuhiko Muraki; David J Beech; Robin S Bon
Journal:  Cells       Date:  2018-06-01       Impact factor: 6.600

10.  Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory.

Authors:  Sophie Lepannetier; Roberta Gualdani; Sabrina Tempesta; Olivier Schakman; François Seghers; Anna Kreis; Xavier Yerna; Amina Slimi; Marie de Clippele; Nicolas Tajeddine; Thomas Voets; Robin S Bon; David J Beech; Fadel Tissir; Philippe Gailly
Journal:  Front Cell Neurosci       Date:  2018-09-14       Impact factor: 5.505
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