Literature DB >> 2839607

Antiviral activity of flavones and potentiation by ascorbate.

R Vrijsen1, L Everaert, A Boeyé.   

Abstract

We compared the anti-poliovirus activities of three flavones, quercetin, luteolin and 3-methylquercetin, which differ only at ring position 3. 3-Methylquercetin was the most potent compound. Quercetin exhibited antiviral activity only when protected against oxidative degradation by ascorbate. The antiviral activity of luteolin was comparable to that of ascorbate-stabilized quercetin.

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Year:  1988        PMID： 2839607     DOI： 10.1099/0022-1317-69-7-1749

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  19 in total

1.  Luteolin, an emerging anti-cancer flavonoid, poisons eukaryotic DNA topoisomerase I.

Authors:  Arnab Roy Chowdhury; Shalini Sharma; Suparna Mandal; Anindya Goswami; Sibabrata Mukhopadhyay; Hemanta K Majumder
Journal:  Biochem J       Date:  2002-09-01       Impact factor: 3.857

Review 2.  Medicinal properties of the Jamaican pepper plant Pimenta dioica and Allspice.

Authors:  Lei Zhang; Bal L Lokeshwar
Journal:  Curr Drug Targets       Date:  2012-12       Impact factor: 3.465

3.  Synthesis and antiviral evaluation of 7-O-arylmethylquercetin derivatives against SARS-associated coronavirus (SCV) and hepatitis C virus (HCV).

Authors:  Hye Ri Park; Hyunjun Yoon; Mi Kyoung Kim; Sung Dae Lee; Youhoon Chong
Journal:  Arch Pharm Res       Date:  2012-02-02       Impact factor: 4.946

4.  Anti-leishmanial and toxicity activities of some selected Iranian medicinal plants.

Authors:  Hamidreza Kheiri Manjili; Hamidreza Jafari; Ali Ramazani; Noushin Davoudi
Journal:  Parasitol Res       Date:  2012-08-09       Impact factor: 2.289

5.  Mechanism of action of the antiherpesvirus biflavone ginkgetin.

Authors:  K Hayashi; T Hayashi; N Morita
Journal:  Antimicrob Agents Chemother       Date:  1992-09       Impact factor: 5.191

6.  The effect of quercetin supplementation on selected markers of inflammation and oxidative stress.

Authors:  Gholamreza Askari; Reza Ghiasvand; Awat Feizi; Syed Mustafa Ghanadian; Jahangir Karimian
Journal:  J Res Med Sci       Date:  2012-07       Impact factor: 1.852

7.  A flavonoid, luteolin, cripples HIV-1 by abrogation of tat function.

Authors:  Rajeev Mehla; Shalmali Bivalkar-Mehla; Ashok Chauhan
Journal:  PLoS One       Date:  2011-11-30       Impact factor: 3.240

8.  Differential induction of Leishmania donovani bi-subunit topoisomerase I-DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I.

Authors:  Benu Brata Das; Nilkantha Sen; Amit Roy; Somdeb Bose Dasgupta; Agneyo Ganguly; Bikash Chandra Mohanta; Biswanath Dinda; Hemanta K Majumder
Journal:  Nucleic Acids Res       Date:  2006-02-18       Impact factor: 16.971

9.  Pedilanthus tithymaloides Inhibits HSV Infection by Modulating NF-κB Signaling.

Authors:  Durbadal Ojha; Rashmi Das; Parveen Sobia; Vedprakash Dwivedi; Soma Ghosh; Amalesh Samanta; Debprasad Chattopadhyay
Journal:  PLoS One       Date:  2015-09-25       Impact factor: 3.240

10.  Identification of luteolin as enterovirus 71 and coxsackievirus A16 inhibitors through reporter viruses and cell viability-based screening.

Authors:  Lin Xu; Weiheng Su; Jun Jin; Jiawen Chen; Xiaojun Li; Xuyuan Zhang; Meiyan Sun; Shiyang Sun; Peihu Fan; Dong An; Huafei Zhang; Xiguang Zhang; Wei Kong; Tonghui Ma; Chunlai Jiang
Journal:  Viruses       Date:  2014-07-17       Impact factor: 5.048
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