Eduardo Ferriolli1, Fernanda Pinheiro Amador Dos Santos Pessanha2, Virgílio Garcia Moreira3, Rosângela Corrêa Dias4, Anita Liberalesso Neri5, Roberto Alves Lourenço6. 1. Division of General Internal and Geriatric Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. Electronic address: eferriol@fmrp.usp.br. 2. Division of General Internal and Geriatric Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. Electronic address: fernandapessanha_fisio@hotmail.com. 3. GeronLab, Internal Medicine Department, Health Science School, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil. Electronic address: virgilio.garcia.moreira@gmail.com. 4. Division of Physiotherapy, School of Physiotherapy, Minas Gerais Federal University, Belo Horizonte, MG, Brazil. Electronic address: rcorreadias8@gmail.com. 5. Department of Internal Medicine, Faculty of Medical Sciences, Campinas State University, Campinas, SP, Brazil. Electronic address: anitalbn@uol.com.br. 6. GeronLab, Internal Medicine Department, Health Science School, Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil. Electronic address: roberto.lourenco@globo.com.
Abstract
OBJECTIVE: To determine the association between body composition and frailty in older Brazilian subjects. MATERIAL AND METHODS: This is a Cross-sectional study called FIBRA-BR and developed in community Brazilian aged ≥65 (n=5638). Frailty was assessed according to Fried et al. definition and body composition was determined by BMI, waist circumference and waist-hip ratio. RESULTS: The lowest prevalence of frailty was observed in subjects with BMI between 25.0 and 29.9kg/m2. Subjects with a BMI <18.5 and those with elevated WC presented a higher risk of frailty compared to eutrophic subjects (odds ratio (OR)=3.10; 95% CI: 2.06-4.67) and (OR=1.15; 95% CI: 1.03-1.27), respectively. Being overweight was protective for pre-frailty (OR=0.48; 95% CI: 0.4-0.58) and frailty (OR=0.77; 95% CI: 0.67-0.9). Obese older people presented a higher risk of pre-frailty only (OR=1.29; 95% CI: 1.09-1.51). Older people with high WC showed a greater proportion of frailty regardless of the BMI range. CONCLUSION: Undernutrition is associated with pre-frailty and frailty in Brazilian elderly subjects, whereas obesity is associated only with pre-frailty. Overweight seems to have a protective effect against the syndrome. The excess of abdominal fat is associated with both profiles independent of the BMI.
OBJECTIVE: To determine the association between body composition and frailty in older Brazilian subjects. MATERIAL AND METHODS: This is a Cross-sectional study called FIBRA-BR and developed in community Brazilian aged ≥65 (n=5638). Frailty was assessed according to Fried et al. definition and body composition was determined by BMI, waist circumference and waist-hip ratio. RESULTS: The lowest prevalence of frailty was observed in subjects with BMI between 25.0 and 29.9kg/m2. Subjects with a BMI <18.5 and those with elevated WC presented a higher risk of frailty compared to eutrophic subjects (odds ratio (OR)=3.10; 95% CI: 2.06-4.67) and (OR=1.15; 95% CI: 1.03-1.27), respectively. Being overweight was protective for pre-frailty (OR=0.48; 95% CI: 0.4-0.58) and frailty (OR=0.77; 95% CI: 0.67-0.9). Obese older people presented a higher risk of pre-frailty only (OR=1.29; 95% CI: 1.09-1.51). Older people with high WC showed a greater proportion of frailty regardless of the BMI range. CONCLUSION: Undernutrition is associated with pre-frailty and frailty in Brazilian elderly subjects, whereas obesity is associated only with pre-frailty. Overweight seems to have a protective effect against the syndrome. The excess of abdominal fat is associated with both profiles independent of the BMI.
Authors: Dhammika D Siriwardhana; Sarah Hardoon; Greta Rait; Manuj C Weerasinghe; Kate R Walters Journal: BMJ Open Date: 2018-03-01 Impact factor: 2.692
Authors: Yukie Nakajima; Steven M Schmidt; Agneta Malmgren Fänge; Mari Ono; Toshiharu Ikaga Journal: Int J Environ Res Public Health Date: 2019-02-20 Impact factor: 3.390
Authors: Mary Ni Lochlainn; Natalie J Cox; Thomas Wilson; Richard P G Hayhoe; Sheena E Ramsay; Antoneta Granic; Masoud Isanejad; Helen C Roberts; Daisy Wilson; Carly Welch; Christopher Hurst; Janice L Atkins; Nuno Mendonça; Katy Horner; Esme R Tuttiett; Yvie Morgan; Phil Heslop; Elizabeth A Williams; Claire J Steves; Carolyn Greig; John Draper; Clare A Corish; Ailsa Welch; Miles D Witham; Avan A Sayer; Sian Robinson Journal: Nutrients Date: 2021-07-09 Impact factor: 5.717