Literature DB >> 28395178

Fluorescent labelling in living cells.

Anselm Fabian Lowell Schneider1, Christian Peter Richard Hackenberger2.   

Abstract

The labelling of proteins with green fluorescent protein enabled the visualization of proteins in living cells for the first time. Since then, much progress has been made in the field. Modern strategies allow the labelling of proteins in live cells through a range of specialized methods with sophisticated chemical probes that show enhanced photophysical properties compared to fluorescent proteins. This review briefly summarizes recent advances in the field of fluorescent chemical protein labelling inside living cells and illustrates key aspects on the requirements and advantages of each given method.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID： 28395178     DOI： 10.1016/j.copbio.2017.03.012

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


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