Marilita M Moschos1, Irini P Chatziralli1. 1. a Electrophysiology Laboratory, 1st Department of Ophthalmology , University of Athens , Athens , Greece.
Abstract
PURPOSE: The purpose of this study was to evaluate retinal and choroidal thickness in patients with Parkinson's disease (PD) using spectral domain-optical coherence tomography (SD-OCT). MATERIAL AND METHODS: Participants in our study were 31 PD patients and 25 age-matched healthy controls. All participants underwent best-corrected visual acuity (BCVA) measurement, slit-lamp biomicroscopy, dilated fundoscopy, and SD-OCT. Macular and retinal nerve fiber layer (RNFL) thickness and choroidal thickness in all quadrants were recorded. RESULTS: There was a statistically significant reduction in average, superior, and temporal RNFL thickness, average ganglion cell complex, and choroidal thickness in the subfoveal area and in all quadrants between patients with PD and controls. CONCLUSIONS: The role of the choroidal vasculature in the pathophysiology of PD should be further scrutinized.
PURPOSE: The purpose of this study was to evaluate retinal and choroidal thickness in patients with Parkinson's disease (PD) using spectral domain-optical coherence tomography (SD-OCT). MATERIAL AND METHODS:Participants in our study were 31 PDpatients and 25 age-matched healthy controls. All participants underwent best-corrected visual acuity (BCVA) measurement, slit-lamp biomicroscopy, dilated fundoscopy, and SD-OCT. Macular and retinal nerve fiber layer (RNFL) thickness and choroidal thickness in all quadrants were recorded. RESULTS: There was a statistically significant reduction in average, superior, and temporal RNFL thickness, average ganglion cell complex, and choroidal thickness in the subfoveal area and in all quadrants between patients with PD and controls. CONCLUSIONS: The role of the choroidal vasculature in the pathophysiology of PD should be further scrutinized.
Authors: Amir H Kashani; Samuel Asanad; Jane W Chan; Maxwell B Singer; Jiong Zhang; Mona Sharifi; Maziyar M Khansari; Farzan Abdolahi; Yonggang Shi; Alessandro Biffi; Helena Chui; John M Ringman Journal: Prog Retin Eye Res Date: 2021-01-15 Impact factor: 19.704
Authors: Jonathon B Young; Pooja Godara; Vesper Williams; Phyllis Summerfelt; Thomas B Connor; Sergey Tarima; Alexis Visotcky; Robert F Cooper; Karen Blindauer; Joseph Carroll Journal: J Neurol Neurophysiol Date: 2019-03-07