Ryosuke Kitoh1, Shin-Ya Nishio1, Kaoru Ogawa2, Sho Kanzaki2, Naohito Hato3, Michihiko Sone4, Satoshi Fukuda5, Akira Hara6, Tetsuo Ikezono7, Kotaro Ishikawa8, Satoshi Iwasaki9, Kimitaka Kaga10, Seiji Kakehata11, Atsushi Matsubara12, Tatsuo Matsunaga10, Takaaki Murata13, Yasushi Naito14, Takashi Nakagawa15, Kazunori Nishizaki16, Yoshihiro Noguchi1, Hajime Sano17, Hiroaki Sato18, Mikio Suzuki19, Hideo Shojaku20, Haruo Takahashi21, Hidehiko Takeda22, Testuya Tono23, Hiroshi Yamashita24, Tatsuya Yamasoba25, Shin-Ichi Usami1. 1. a Department of Otorhinolaryngology , Shinshu University School of Medicine , Matsumoto , Japan. 2. b Department of Otorhinolaryngology Head and Neck Surgery , Keio University School of Medicine , Tokyo , Japan. 3. c Department of Otolaryngology , Ehime University School of Medicine , Toon , Japan. 4. d Department of Otorhinolaryngology , Nagoya University, Graduate School of Medicine , Nagoya , Japan. 5. e Department of Otolaryngology-Head and Neck Surgery , Hokkaido University Graduate School of Medicine , Sapporo , Japan. 6. f Department of Otolaryngology, Faculty of Medicine , University of Tsukuba , Tsukuba , Japan. 7. g Department of Otorhinolaryngology , Saitama School of medicine , Moroyama , Japan. 8. h Department of Otolaryngology, Hospital , National Rehabilitation Center for Persons with Disabilities , Tokorozawa , Japan. 9. i Department of Otolaryngology , International University of Health and Welfare, Mita Hospital , Tokyo , Japan. 10. j Division of Hearing and Balance Research , National Institute of Sensory Organs, National Hospital Organization Tokyo Medical Center , Tokyo , Japan. 11. k Department of Otorhinolaryngology , Yamagata University School of Medicine , Yamagata , Japan. 12. l Department of Otorhinolaryngology , Hirosaki University Graduate School of Medicine , Hirosaki , Japan. 13. m Department of Otolaryngology , Gunma University Graduate School of Medicine , Maebashi , Japan. 14. n Department of Otolaryngology , Kobe City Medical Center General Hospital , Kobe , Japan. 15. o Department of Otorhinolaryngology , Kyushu University Graduate School of Medical Sciences , Fukuoka , Japan. 16. p Department of Otolaryngology-Head and Neck Surgery , Okayama University Graduate School of Medicine, Dentistry and Pharmacy , Okayama , Japan. 17. q Department of Otolaryngology , Kitasato University School of Medicine , Sagamihara , Japan. 18. r Department of Otorhinolaryngology , Iwate Medical University , Morioka , Japan. 19. s Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Medicine , University of the Ryukyus , Nishihara , Japan. 20. t Department of Otorhinolaryngology, Head and Neck Surgery , University of Toyama , Toyama , Japan. 21. u Department of Otolaryngology , Nagasaki University Faculty of Medicine , Nagasaki , Japan. 22. v Department of Otolaryngology , Okinaka Memorial Institute for Medical Research, Toranomon Hospital , Tokyo , Japan. 23. w Department of Otolaryngology, Faculty of Medicine , University of Miyazaki , Miyazaki , Japan. 24. x Department of Otolaryngology , Yamaguchi University Graduate School of Medicine , Ube , Japan. 25. y Department of Otolaryngology, Faculty of Medicine , University of Tokyo , Tokyo , Japan.
Abstract
OBJECTIVES: Using a large-scale nationwide survey database, we investigated the epidemiological characteristics for idiopathic SSNHL in Japan. METHODS: The subjects for this analysis were patients registered in a Japanese multicentre database between April 2014 and March 2016. A total of 3419 idiopathic SSNHL patients were registered in the database, and the clinical characteristics of the idiopathic SSNHL patients were obtained. Several factors associated with the severity of hearing impairment and prognosis were then investigated. Statistical analysis was performed to clarify the factors associated with the severity of hearing impairment and prognosis. RESULTS: There were significant correlations between the severity of hearing loss and diabetes mellitus, kidney disease, past history of brain infarction, heart disease, age (under 16 years/elderly), and symptoms of vertigo/dizziness. We also analyzed the prognostic factors for idiopathic SSNHL, and found that the severity of hearing loss (Grade 3 or 4), heart disease, aged 65 years or over, time from onset to treatment (over 7 days), and symptoms of vertigo/dizziness were all significantly related to poor prognosis. CONCLUSION: The present large-scale clinical survey revealed current epidemiological trends for idiopathic sudden sensorineural hearing loss (SSNHL) and various factors associated with the severity of hearing impairment and prognosis.
OBJECTIVES: Using a large-scale nationwide survey database, we investigated the epidemiological characteristics for idiopathic SSNHL in Japan. METHODS: The subjects for this analysis were patients registered in a Japanese multicentre database between April 2014 and March 2016. A total of 3419 idiopathic SSNHL patients were registered in the database, and the clinical characteristics of the idiopathic SSNHL patients were obtained. Several factors associated with the severity of hearing impairment and prognosis were then investigated. Statistical analysis was performed to clarify the factors associated with the severity of hearing impairment and prognosis. RESULTS: There were significant correlations between the severity of hearing loss and diabetes mellitus, kidney disease, past history of brain infarction, heart disease, age (under 16 years/elderly), and symptoms of vertigo/dizziness. We also analyzed the prognostic factors for idiopathic SSNHL, and found that the severity of hearing loss (Grade 3 or 4), heart disease, aged 65 years or over, time from onset to treatment (over 7 days), and symptoms of vertigo/dizziness were all significantly related to poor prognosis. CONCLUSION: The present large-scale clinical survey revealed current epidemiological trends for idiopathic sudden sensorineural hearing loss (SSNHL) and various factors associated with the severity of hearing impairment and prognosis.