Literature DB >> 28393688

Nanoscale Functional Biomaterials for Cancer Theranostics.

Linying Liu1,2, Xiaoshuang Li3, Lei Chen3, Xin Zhang1.   

Abstract

Nanomedicine is widely developed in recent years. In nanomedicine system, nanoscale and nanostructured functional materials are used to manipulate the human biology systems at the molecular level for cancer imaging and therapy. New nanostructure based functional materials consist of nanoscale liposomes, spheres, micelles, capsules, emulsion, suspension and phamacosomes. Several functional nanoparticles such as lipidbased and polymer-based materials are demonstrated to be drug delivery vehicles and imaging agents. These materials are biodegradable, biocompatible and have better biodistribution, lower side effect and lower toxicity. In addition, hybrids with these materials coating provide uniquely electrical, optical and magnetic properties. This review discusses the research on the applications of functional materials, especially nanoparticles as imaging contrast agents, cancer therapeutic agents and multi-functional agents and this review focused on the theranostic integration treatments on liver cancer and brain cancer. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Nanomaterials; biomaterials; cancer; gliomatosis cerebri; imaging; liver tumor; theranostics; therapy.

Mesh:

Substances:

Year:  2018        PMID: 28393688     DOI: 10.2174/0929867324666170406111036

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN: 0929-8673            Impact factor:   4.530


  4 in total

1.  A novel oral micellar fenretinide formulation with enhanced bioavailability and antitumour activity against multiple tumours from cancer stem cells.

Authors:  Isabella Orienti; Valentina Salvati; Giovanni Sette; Massimo Zucchetti; Lucilla Bongiorno-Borbone; Angelo Peschiaroli; Lello Zolla; Federica Francescangeli; Mariella Ferrari; Cristina Matteo; Ezia Bello; Antonio Di Virgilio; Mario Falchi; Maria Laura De Angelis; Marta Baiocchi; Gerry Melino; Ruggero De Maria; Ann Zeuner; Adriana Eramo
Journal:  J Exp Clin Cancer Res       Date:  2019-08-22

2.  Tumor-targeted Gd-doped mesoporous Fe3O4 nanoparticles for T1/T2 MR imaging guided synergistic cancer therapy.

Authors:  Shaohui Zheng; Shang Jin; Min Jiao; Wenjun Wang; Xiaoyu Zhou; Jie Xu; Yong Wang; Peipei Dou; Zhen Jin; Changyu Wu; Jingjing Li; Xinting Ge; Kai Xu
Journal:  Drug Deliv       Date:  2021-12       Impact factor: 6.419

3.  A Unique Core-Shell Structured, Glycol Chitosan-Based Nanoparticle Achieves Cancer-Selective Gene Delivery with Reduced Off-Target Effects.

Authors:  Bei Cheng; Hye-Hyun Ahn; Hwanhee Nam; Zirui Jiang; Feng J Gao; Il Minn; Martin G Pomper
Journal:  Pharmaceutics       Date:  2022-02-07       Impact factor: 6.525

Review 4.  Theranostics Based on Magnetic Nanoparticles and Polymers: Intelligent Design for Efficient Diagnostics and Therapy.

Authors:  Andrew J Gauger; Kian K Hershberger; Lyudmila M Bronstein
Journal:  Front Chem       Date:  2020-07-07       Impact factor: 5.221

  4 in total

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