Hanan H Balkhy1, Kamel El Beltagy2, Aiman El-Saed3, Badr Aljasir4, Abdulhakeem Althaqafi5, Adel F Alothman6, Mohammad Alshalaan7, Hamdan Al-Jahdali6. 1. King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Kingdom of Saudi Arabia; King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Kingdom of Saudi Arabia; Infection Prevention and Control Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Saudi Arabia. Electronic address: balkhyh@hotmail.com. 2. Infection Prevention and Control Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Saudi Arabia; Public health & Community Medicine Department, Faculty of Medicine, Tanta University, Egypt. 3. Infection Prevention and Control Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Saudi Arabia; Public health & Community Medicine Department, Faculty of Medicine, Mansoura University, Egypt. 4. King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Kingdom of Saudi Arabia; Preventive Medicine Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Saudi Arabia. 5. King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Kingdom of Saudi Arabia; Infection Prevention and Control Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Saudi Arabia. 6. King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Kingdom of Saudi Arabia; Department of Medicine, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Saudi Arabia. 7. King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Kingdom of Saudi Arabia; Department of Pediatrics, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Saudi Arabia.
Abstract
BACKGROUND: The annual risk of tuberculosis infection (ARTI) data in Saudi Arabia has not been updated since 1993. OBJECTIVES: To estimate the prevalence of latent TB infection (LTBI) and ARTI in a population-based sample in Saudi Arabia using Tuberculin skin test (TST) and QuantiFERON TB Gold in tube (QFT-GIT) test. METHODS: A population-based cross sectional study was conducted between July 2010 and March 2013. Participants were randomly selected from the population served by the primary healthcare centers of the Ministry of National Guard Health Affairs in Riyadh, Jeddah, Alhassa and Dammam, Saudi Arabia. RESULTS: A total of 1369 participants were included. The overall prevalence of LTBI was similar using TST and QFT-GIT (9.3% and 9.1% respectively, p=0.872) but stratified prevalence rates were variable in all sociodemographic groups except marital status. Additionally, the prevalence rates of LTBI using either test alone showed significant differences by several sociodemographic and behavioral characteristics. The overall ARTI was 0.36% using TST and 0.35% using QFT-GIT. CONCLUSIONS: We are reporting much lower estimates for the prevalence of LTBI and the ARTI in a population-based sample in Saudi Arabia relative to the data that have been used for more than two decades.
BACKGROUND: The annual risk of tuberculosis infection (ARTI) data in Saudi Arabia has not been updated since 1993. OBJECTIVES: To estimate the prevalence of latent TB infection (LTBI) and ARTI in a population-based sample in Saudi Arabia using Tuberculin skin test (TST) and QuantiFERON TB Gold in tube (QFT-GIT) test. METHODS: A population-based cross sectional study was conducted between July 2010 and March 2013. Participants were randomly selected from the population served by the primary healthcare centers of the Ministry of National Guard Health Affairs in Riyadh, Jeddah, Alhassa and Dammam, Saudi Arabia. RESULTS: A total of 1369 participants were included. The overall prevalence of LTBI was similar using TST and QFT-GIT (9.3% and 9.1% respectively, p=0.872) but stratified prevalence rates were variable in all sociodemographic groups except marital status. Additionally, the prevalence rates of LTBI using either test alone showed significant differences by several sociodemographic and behavioral characteristics. The overall ARTI was 0.36% using TST and 0.35% using QFT-GIT. CONCLUSIONS: We are reporting much lower estimates for the prevalence of LTBI and the ARTI in a population-based sample in Saudi Arabia relative to the data that have been used for more than two decades.
Authors: Abdulellah Almohaya; Abdulwahab Aldrees; Layan Akkielah; Alshaima Talal Hashim; Fahad Almajid; Turki Binmoammar; Mazin A Barry Journal: Ann Saudi Med Date: 2020-06-04 Impact factor: 1.526
Authors: Hani S Almugti; Hussam M Alfaleh; Turki M Alshehri; Khaled Q Mokili; Abdul-Aziz M Al Qahtani; Hassan S Al Qahtani; Mohammed Z Alsayed; Mohammed A Al Asmari; Majed M Al Asiri; Mohammed A Al Amri; Ali F Al Fadhil; Bairam A Al Qahtani; Esmaeel S Al Bakrah; Humood A Shaikh; Mohammed G Al Shiq; Yahya A Al Shaik Journal: Cureus Date: 2022-09-13