Literature DB >> 28391843

A novel mitochondria-targeted near-infrared fluorescence probe for ultrafast and ratiometric detection of SO2 derivatives in live cells.

Hui Huang1, Wei Liu2, Xian-Jun Liu1, Yong-Qing Kuang3, Jian-Hui Jiang1.   

Abstract

A novel mitochondria-targeted ratiometric near-infrared fluorescence probe NDMBT for Sulfur dioxide (SO2) derivatives was constructed based on the SO2 derivatives-triggered Michael addition reaction. It displayed ultrafast response time (within 10s), large hypsochromic shift (260nm), high photostability, excellent selectivity and high sensitivity in aqueous media with a detection limit of 43nM. More importantly, it was successfully applied to imaging of the enzymatically generated SO2 derivatives in mitochondria of live cells.
Copyright © 2017. Published by Elsevier B.V.

Entities:  

Keywords:  Mitochondria-targeted; Near-infrared fluorescence probe; Ratiometric fluorescence detection; SO(2) derivatives

Mesh：

Substances：

Year:  2017        PMID： 28391843     DOI： 10.1016/j.talanta.2017.03.043

Source DB:  PubMed          Journal:  Talanta        ISSN： 0039-9140            Impact factor:   6.057


  3 in total

Review 1.  Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives.

Authors:  Gantumur Battogtokh; Yeon Su Choi; Dong Seop Kang; Sang Jun Park; Min Suk Shim; Kang Moo Huh; Yong-Yeon Cho; Joo Young Lee; Hye Suk Lee; Han Chang Kang
Journal:  Acta Pharm Sin B       Date:  2018-05-18       Impact factor: 11.413

2.  A Ratiometric and Colorimetric Hemicyanine Fluorescent Probe for Detection of SO2 Derivatives and Its Applications in Bioimaging.

Authors:  Yan-Hong Qin; Xiao-Yi Jiang; Yuan-Fang Que; Jing-Yi Gu; Tong Wu; Ayinazhaer Aihemaiti; Ke-Xin Shi; Wen-Yu Kang; Bi-Ying Hu; Jin-Shuai Lan; Yue Ding; Tong Zhang
Journal:  Molecules       Date:  2019-11-05       Impact factor: 4.411

3.  A ratiometric fluorescent probe for detection of exogenous mitochondrial SO2 based on a FRET mechanism.

Authors:  Zhiyang Xu; Zhen Chen; Aikun Liu; Ruixue Ji; Xiaoqun Cao; Yanqing Ge
Journal:  RSC Adv       Date:  2019-03-18       Impact factor: 3.361
  3 in total

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