| Literature DB >> 28391784 |
Tetsuya Akaishi1, Ichiro Nakashima1, Douglas Kazutoshi Sato2, Toshiyuki Takahashi3, Kazuo Fujihara4.
Abstract
Neuromyelitis optica (NMO) is clinically characterized by severe optic neuritis and transverse myelitis, but recent studies with anti-aquaporin-4-antibody specific to NMO have revealed that the clinical spectrum is wider than previously thought. International consensus diagnostic criteria propose NMO spectrum disorders (NMOSD) as the term to define the entire spectrum including typical NMO, optic neuritis, acute myelitis, brain syndrome, and their combinations. NMOSD is now divided into anti-aquaporin-4-antibody-seropositive NMOSD and -seronegative NMOSD (or unknown serostatus). MR imaging and optical coherence tomography are indispensable in the diagnosis and evaluation of NMOSD. This article reviews the clinical and MR imaging findings of anti-aquaporin-4-antibody-seropositive and anti-myelin oligodendrocyte glycoprotein-antibody-seropositive NMOSD.Entities:
Keywords: Anti-aquaporin-4 antibody; Anti-myelin oligodendrocyte glycoprotein antibody; MR imaging; Neuromyelitis optica spectrum disorders; Optical coherence tomography
Mesh:
Substances:
Year: 2017 PMID: 28391784 DOI: 10.1016/j.nic.2016.12.010
Source DB: PubMed Journal: Neuroimaging Clin N Am ISSN: 1052-5149 Impact factor: 2.264