Literature DB >> 28390888

Liposomal Bupivacaine Mixture Has Similar Pain Relief and Significantly Fewer Complications at Less Cost Compared to Indwelling Interscalene Catheter in Total Shoulder Arthroplasty.

William J Weller1, Michael G Azzam1, Richard A Smith1, Frederick M Azar1, Thomas W Throckmorton1.   

Abstract

BACKGROUND: The efficacy and costs of indwelling interscalene catheter (ISC) and liposomal bupivacaine (LBC), with and without adjunctive medications, in patients with primary shoulder arthroplasty are a source of current debate.
METHODS: In 214 arthroplasties, 156 patients had ISC and 58 had LBC injections that were mixed with morphine, ketorolac, and 0.5% bupivacaine with epinephrine. Charts were reviewed for visual analog scale pain scores, oral morphine equivalent (OME) usage, major complications, and costs.
RESULTS: Visual analog scale scores were not significantly different at 24 hours or at 2, 6, and 12 weeks. Average OME consumption at 24 hours was significantly more with LBC, but was not significantly different at 12 weeks. Relative risk of a major complication was nearly 4 times higher with ISC than with LBC. The average cost for the LBC mixture was $289.04, and for ISC, including equipment and anesthesia fees, was $1559.42.
CONCLUSION: The intraoperative LBC mixture provided equivalent pain relief with significantly fewer major complications and at markedly lower cost than ISC. LBC required almost twice as much OME to attain the same level of pain relief at 24 hours, but there was no significant difference in the cumulative amount of outpatient narcotic use.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  complications; cost analysis; interscalene catheter; liposomal bupivacaine; total shoulder arthroplasty

Mesh:

Substances:

Year:  2017        PMID: 28390888     DOI: 10.1016/j.arth.2017.03.017

Source DB:  PubMed          Journal:  J Arthroplasty        ISSN: 0883-5403            Impact factor:   4.757


  8 in total

Review 1.  Current Status Regarding the Safety of Inpatient Versus Outpatient Total Shoulder Arthroplasty: A Systematic Review.

Authors:  Richard N Puzzitiello; Michael A Moverman; Nicholas R Pagani; Mariano E Menendez; Matthew J Salzler
Journal:  HSS J       Date:  2021-07-05

2.  Single-shot liposomal bupivacaine interscalene block versus continuous interscalene catheter in total shoulder arthroplasty: Opioid administration, pain scores, and complications.

Authors:  Tristan B Weir; Nana Simpson; Ali Aneizi; Michael J Foster; Julio J Jauregui; Mohit N Gilotra; R Frank Henn Iii; S Ashfaq Hasan
Journal:  J Orthop       Date:  2020-05-11

3.  The efficacy and safety of interscalene blockade versus local infiltration analgesia in primary total shoulder arthroplasty?: A protocol for systematic review and meta-analysis of randomized controlled trials.

Authors:  Yanhui Wu; Yuan Chen; Cheng Ji; Wen Ye
Journal:  Medicine (Baltimore)       Date:  2021-03-26       Impact factor: 1.817

Review 4.  Liposomal bupivacaine versus interscalene nerve block for pain control after shoulder arthroplasty: A meta-analysis.

Authors:  Zeng Yan; Zong Chen; Chuangen Ma
Journal:  Medicine (Baltimore)       Date:  2017-07       Impact factor: 1.889

Review 5.  Do liposomal bupivacaine infiltration and interscalene nerve block provide similar pain relief after total shoulder arthroplasty: a systematic review and meta-analysis.

Authors:  Han Sun; Shuxiang Li; Kun Wang; Jian Zhou; Guofeng Wu; Sheng Fang; Xiaoliang Sun
Journal:  J Pain Res       Date:  2018-09-18       Impact factor: 3.133

6.  Efficacy of local infiltration anesthesia versus interscalene nerve blockade for total shoulder arthroplasty.

Authors:  Gary F Updegrove; Christopher M Stauch; Padmavathi Ponnuru; Allen R Kunselman; April D Armstrong
Journal:  JSES Int       Date:  2020-03-03

7.  Interscalene Block for Analgesia in Orthopedic Treatment of Shoulder Trauma: Single-Dose Liposomal Bupivacaine versus Perineural Catheter.

Authors:  Andrzej P Kwater; Nadia Hernandez; Carlos Artime; Johanna Blair de Haan
Journal:  Local Reg Anesth       Date:  2021-12-07

8.  Sustained-release lidocaine sheet for pain following tooth extraction: A randomized, single-blind, dose-response, controlled, clinical study of efficacy and safety.

Authors:  Toshiyuki Suzuki; Kensuke Kosugi; Takashi Suto; Masaru Tobe; Yasuhiko Tabata; Satoshi Yokoo; Shigeru Saito
Journal:  PLoS One       Date:  2018-07-02       Impact factor: 3.240

  8 in total

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