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Literature DB >> 28389505

OnabotulinumtoxinA injections in detrusor facilitate self-catheterisation in a patient with paraplegia and bladder outlet dyssynergia.

François Hervé¹, Annick Viaene², Karel Everaert³.

Abstract

This case report describes the case of improvement of clean intermittent catheterisation procedures after each intradetrusor administration of onabotulinumtoxinA in a 45-year-old man with L1 paraplegia with neurogenic detrusor overactivity and bladder outlet dyssynergia.On three occasions, improvement on clean intermittent catheterisation procedures appeared 10 to 14 days after intradetrusor injections of onabotulinumtoxinA and lasted for 9 months. We hypothesise a possible influence of intravesical injections of onabotulinumtoxinA on the storage reflex. We also discuss the possibility of a dispersion of onabotulinumtoxinA towards contiguous structures such as the urethral sphincter. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities: Disease Species

Keywords: Catheter care; Drugs and medicines; Neurological injury; Neurology, Continence; Neurology, Spinal cord; Urinary and genital tract disorder; Urology

Mesh：

Substances：
Botulinum Toxins, Type A

Year: 2017 PMID： 28389505 PMCID： PMC5534778 DOI： 10.1136/bcr-2016-218429

Source DB: PubMed Journal: BMJ Case Rep ISSN： 1757-790X

Keyword Cloud
References

13 in total

Review 1. Neural control of the urethra.

Authors: W C de Groat; M O Fraser; M Yoshiyama; S Smerin; C Tai; M B Chancellor; N Yoshimura; J R Roppolo
Journal: Scand J Urol Nephrol Suppl Date: 2001

Review 2. The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society.

Authors: Paul Abrams; Linda Cardozo; Magnus Fall; Derek Griffiths; Peter Rosier; Ulf Ulmsten; Philip Van Kerrebroeck; Arne Victor; Alan Wein
Journal: Urology Date: 2003-01 Impact factor: 2.649

3. Side effects of intradetrusor botulinum toxin injections on ejaculation and fertility in men with spinal cord injury: preliminary findings.

Authors: Romain Caremel; Frédérique Courtois; Kathleen Charvier; Alain Ruffion; Nicolas Morel Journel
Journal: BJU Int Date: 2011-10-07 Impact factor: 5.588

4. A multicenter, randomized, double-blind, placebo controlled study of onabotulinumtoxinA 200 U to treat lower urinary tract symptoms in men with benign prostatic hyperplasia.

Authors: Kevin T McVary; Claus G Roehrborn; Emmanuel Chartier-Kastler; Mitchell Efros; Denise Bugarin; Ru Chen; Anand Patel; Cornelia Haag-Molkenteller
Journal: J Urol Date: 2014-02-07 Impact factor: 7.450

5. Results of a prospective, randomized, multicenter study evaluating sacral neuromodulation with InterStim therapy compared to standard medical therapy at 6-months in subjects with mild symptoms of overactive bladder.

Authors: Steven Siegel; Karen Noblett; Jeffrey Mangel; Tomas L Griebling; Suzette E Sutherland; Erin T Bird; Craig Comiter; Daniel Culkin; Jason Bennett; Samuel Zylstra; Kellie Chase Berg; Fangyu Kan; Christopher P Irwin
Journal: Neurourol Urodyn Date: 2014-01-10 Impact factor: 2.696

Review 6. Botulinum toxin A (Botox) intradetrusor injections in adults with neurogenic detrusor overactivity/neurogenic overactive bladder: a systematic literature review.

Authors: Gilles Karsenty; Pierre Denys; Gérard Amarenco; Marianne De Seze; Xavier Gamé; François Haab; Jacques Kerdraon; Brigitte Perrouin-Verbe; Alain Ruffion; Christian Saussine; Jean-Marc Soler; Brigitte Schurch; Emmanuel Chartier-Kastler
Journal: Eur Urol Date: 2007-10-16 Impact factor: 20.096

OnabotulinumtoxinA injections in detrusor facilitate self-catheterisation in a patient with paraplegia and bladder outlet dyssynergia.

Review 1. Neural control of the urethra.

Review 2. The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society.

3. Side effects of intradetrusor botulinum toxin injections on ejaculation and fertility in men with spinal cord injury: preliminary findings.

4. A multicenter, randomized, double-blind, placebo controlled study of onabotulinumtoxinA 200 U to treat lower urinary tract symptoms in men with benign prostatic hyperplasia.

5. Results of a prospective, randomized, multicenter study evaluating sacral neuromodulation with InterStim therapy compared to standard medical therapy at 6-months in subjects with mild symptoms of overactive bladder.

Review 6. Botulinum toxin A (Botox) intradetrusor injections in adults with neurogenic detrusor overactivity/neurogenic overactive bladder: a systematic literature review.

7. Detrusor bladder neck dyssynergia revisited.

Review 8. Botulinum toxin as a new therapy option for voiding disorders: current state of the art.

Review 9. The role of botulinum toxin A in treating neurogenic bladder.

Review 10. Botulinum Toxin A and Lower Urinary Tract Dysfunction: Pathophysiology and Mechanisms of Action.