| Literature DB >> 28389382 |
Tanja Dragojević1, Hari M Varma2, Joseph L Hollmann2, Claudia P Valdes2, Joseph P Culver3, Carles Justicia4, Turgut Durduran5.
Abstract
High-density speckle contrast optical tomography (SCOT) utilizing tens of thousands of source-detector pairs, was developed for in vivo imaging of blood flow in small animals. The reduction in cerebral blood flow (CBF) due to local ischemic stroke in a mouse brain was transcanially imaged and reconstructed in three dimensions. The reconstructed volume was then compared with corresponding magnetic resonance images demonstrating that the volume of reduced CBF agrees with the infarct zone at twenty-four hours.Entities:
Keywords: (110.3010) Image reconstruction techniques; (110.6150) Speckle imaging; (170.3880) Medical and biological imaging; OCIS codes
Mesh:
Year: 2017 PMID: 28389382 DOI: 10.1016/j.neuroimage.2017.04.003
Source DB: PubMed Journal: Neuroimage ISSN: 1053-8119 Impact factor: 6.556