Literature DB >> 28387643

Novel GOPC(FIG)-ROS1 fusion in a pediatric high-grade glioma survivor.

Erin N Kiehna1, Maxine R Arnush2, Benita Tamrazi3, Jennifer A Cotter4,5, Debra Hawes4, Nathan J Robison6, Cindy Y Fong4, Dolores B Estrine4, Jennifer H Han4, Jaclyn A Biegel4,5.   

Abstract

Pediatric high-grade glioma is a rare tumor characterized by high mortality. The authors report the first case of a high-grade glioma associated with a GOPC(FIG)-ROS1 fusion in a pediatric patient. The patient underwent gross-total resection at the age of 4 years, followed by adjuvant high-dose chemotherapy and autologous hematopoietic stem cell rescue. At 30 months after transplantation, she remains disease free.

Entities:  

Keywords:  6q22 deletion; CNS = central nervous system; FFPE = formalin-fixed, paraffin-embedded; GOPC; ROS1; RT-PCR = reverse transcriptase–polymerase chain reaction; RTK = receptor tyrosine kinase; oncology; receptor protein-tyrosine kinases

Mesh：

Substances：

Year:  2017        PMID： 28387643     DOI： 10.3171/2017.2.PEDS16679

Source DB:  PubMed          Journal:  J Neurosurg Pediatr        ISSN： 1933-0707            Impact factor:   2.375


  7 in total

1.  Successful Treatment of Patients with Refractory High-Grade Serous Ovarian Cancer with GOPC-ROS1 Fusion Using Crizotinib: A Case Report.

Authors:  Dapeng Dong; Ge Shen; Yong Da; Ming Zhou; Gang Yang; Mingming Yuan; Rongrong Chen
Journal:  Oncologist       Date:  2020-07-25

2.  Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.

Authors:  Matthew Clarke; Alan Mackay; Britta Ismer; Jessica C Pickles; Ruth G Tatevossian; Scott Newman; Tejus A Bale; Iris Stoler; Elisa Izquierdo; Sara Temelso; Diana M Carvalho; Valeria Molinari; Anna Burford; Louise Howell; Alex Virasami; Amy R Fairchild; Aimee Avery; Jane Chalker; Mark Kristiansen; Kelly Haupfear; James D Dalton; Wilda Orisme; Ji Wen; Michael Hubank; Kathreena M Kurian; Catherine Rowe; Mellissa Maybury; Stephen Crosier; Jeffrey Knipstein; Ulrich Schüller; Uwe Kordes; David E Kram; Matija Snuderl; Leslie Bridges; Andrew J Martin; Lawrence J Doey; Safa Al-Sarraj; Christopher Chandler; Bassel Zebian; Claire Cairns; Rachael Natrajan; Jessica K R Boult; Simon P Robinson; Martin Sill; Ira J Dunkel; Stephen W Gilheeney; Marc K Rosenblum; Debbie Hughes; Paula Z Proszek; Tobey J Macdonald; Matthias Preusser; Christine Haberler; Irene Slavc; Roger Packer; Ho-Keung Ng; Shani Caspi; Mara Popović; Barbara Faganel Kotnik; Matthew D Wood; Lissa Baird; Monika Ashok Davare; David A Solomon; Thale Kristin Olsen; Petter Brandal; Michael Farrell; Jane B Cryan; Michael Capra; Michael Karremann; Jens Schittenhelm; Martin U Schuhmann; Martin Ebinger; Winand N M Dinjens; Kornelius Kerl; Simone Hettmer; Torsten Pietsch; Felipe Andreiuolo; Pablo Hernáiz Driever; Andrey Korshunov; Lotte Hiddingh; Barbara C Worst; Dominik Sturm; Marc Zuckermann; Olaf Witt; Tabitha Bloom; Clare Mitchell; Evelina Miele; Giovanna Stefania Colafati; Francesca Diomedi-Camassei; Simon Bailey; Andrew S Moore; Timothy E G Hassall; Stephen P Lowis; Maria Tsoli; Mark J Cowley; David S Ziegler; Matthias A Karajannis; Kristian Aquilina; Darren R Hargrave; Fernando Carceller; Lynley V Marshall; Andreas von Deimling; Christof M Kramm; Stefan M Pfister; Felix Sahm; Suzanne J Baker; Angela Mastronuzzi; Andrea Carai; Maria Vinci; David Capper; Sergey Popov; David W Ellison; Thomas S Jacques; David T W Jones; Chris Jones
Journal:  Cancer Discov       Date:  2020-04-01       Impact factor: 39.397

3.  Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas.

Authors:  Ana S Guerreiro Stucklin; Scott Ryall; Kohei Fukuoka; Michal Zapotocky; Alvaro Lassaletta; Christopher Li; Taylor Bridge; Byungjin Kim; Anthony Arnoldo; Paul E Kowalski; Yvonne Zhong; Monique Johnson; Claire Li; Arun K Ramani; Robert Siddaway; Liana Figueiredo Nobre; Pasqualino de Antonellis; Christopher Dunham; Sylvia Cheng; Daniel R Boué; Jonathan L Finlay; Scott L Coven; Inmaculada de Prada; Marta Perez-Somarriba; Claudia C Faria; Michael A Grotzer; Elisabeth Rushing; David Sumerauer; Josef Zamecnik; Lenka Krskova; Miguel Garcia Ariza; Ofelia Cruz; Andres Morales La Madrid; Palma Solano; Keita Terashima; Yoshiko Nakano; Koichi Ichimura; Motoo Nagane; Hiroaki Sakamoto; Maria Joao Gil-da-Costa; Roberto Silva; Donna L Johnston; Jean Michaud; Bev Wilson; Frank K H van Landeghem; Angelica Oviedo; P Daniel McNeely; Bruce Crooks; Iris Fried; Nataliya Zhukova; Jordan R Hansford; Amulya Nageswararao; Livia Garzia; Mary Shago; Michael Brudno; Meredith S Irwin; Ute Bartels; Vijay Ramaswamy; Eric Bouffet; Michael D Taylor; Uri Tabori; Cynthia Hawkins
Journal:  Nat Commun       Date:  2019-09-25       Impact factor: 14.919

4.  Clinical management and genomic profiling of pediatric low-grade gliomas in Saudi Arabia.

Authors:  Nahla A Mobark; Musa Alharbi; Lamees Alhabeeb; Latifa AlMubarak; Rasha Alaljelaify; Mariam AlSaeed; Amal Almutairi; Fatmah Alqubaishi; Maqsood Ahmad; Ayman Al-Banyan; Fahad E Alotabi; Duna Barakeh; Malak AlZahrani; Hisham Al-Khalidi; Abdulrazag Ajlan; Lori A Ramkissoon; Shakti H Ramkissoon; Malak Abedalthagafi
Journal:  PLoS One       Date:  2020-01-29       Impact factor: 3.240

5.  Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers.

Authors:  Zhonghua Tao; Jianxia Liu; Ting Li; Hong Xu; Kai Chen; Jian Zhang; Hao Zhou; Jie Sun; Jinming Han; Zhaoji Guo; Hua Yang; Wen-Ming Cao; Xichun Hu
Journal:  Front Oncol       Date:  2021-09-28       Impact factor: 6.244

Review 6.  The oncogenic fusion landscape in pediatric CNS neoplasms.

Authors:  Mieke Roosen; Zelda Odé; Jens Bunt; Marcel Kool
Journal:  Acta Neuropathol       Date:  2022-02-15       Impact factor: 15.887

Review 7.  Mechanisms of receptor tyrosine kinase activation in cancer.

Authors:  Zhenfang Du; Christine M Lovly
Journal:  Mol Cancer       Date:  2018-02-19       Impact factor: 27.401
  7 in total

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