| Literature DB >> 28387433 |
Takato Morioka1, Nobuya Murakami1, Takafumi Shimogawa1,2, Nobutaka Mukae2, Kimiakai Hashiguchi2, Satoshi O Suzuki3, Koji Iihara2.
Abstract
Lumbosacral lipomas are the most common form of occult spinal dysraphism. The development of lumbosacral lipomas is from the premature disjunction of the neural tube from the surrounding ectoderm, leaving the neural plate open posteriorly and allowing for the infiltration of mesodermal tissue, including fatty tissue. Since lumbosacral lipomas are a common cause of spinal cord tethering that can lead to progressive neurological deficits, prophylactic neurosurgery for lumbosacral lipomas, including untethering of the spinal cord, is recommended. We briefly review the embryology, classification, clinical presentation, imaging evaluation, surgical indication, neurosurgical management and pathological examination that are involved in recognizing these complicated malformative pathologies.Entities:
Keywords: lumbosacral lipomas; occult spinal dysraphism; premature disjunction; tethered cord; untethering
Mesh:
Year: 2017 PMID: 28387433 DOI: 10.1111/neup.12382
Source DB: PubMed Journal: Neuropathology ISSN: 0919-6544 Impact factor: 1.906