| Literature DB >> 28387393 |
Seonghoon Kim1, HyeongChan Jo2, Mijeong Jeon2, Myung-Gyu Choi3, Sei Kwang Hahn4, Seok-Hyun Yun1.
Abstract
Conjugates of Rose Bengal and Renilla luciferase generated singlet oxygen upon binding with coelenterazine via bioluminescence resonance energy transfer (BRET). Since the applications of conventional PDT have been limited to superficial lesions due to the limited light penetration in tissue, BRET activated PDT which does not require external light illumination may overcome the limitations of conventional PDT.Entities:
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Year: 2017 PMID: 28387393 PMCID: PMC5489260 DOI: 10.1039/c7cc00041c
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222