| Literature DB >> 28387 |
M G Bramble, J Cunliffe, A W Dellipiani.
Abstract
In a study of oesophageal motility in 20 patients with Parkinson's disease, intravenous atropine produced marked disruption of co-ordination in response to swallows, when compared with control subjects. This suggests that cholinergic rather than dopaminergic mechanisms are more important in the control of swallowing in patients with Parkinsonism. No conclusive evidence of peripheral dopamine depletion or autonomic neuropathy was found, although minor changes suggestive of the former were found in severely affected patients.Entities:
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Year: 1978 PMID： 28387 PMCID： PMC1083386 DOI： 10.1136/jnnp.41.8.709
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154