Literature DB >> 28386402

Opioid-induced myoclonus and hyperalgesia following a short course of low-dose oral morphine.

Owen Bleddyn Woodward1, Sangeeta Naraen1, Akriti Naraen1.   

Abstract

A 76-year-old man was admitted to hospital with a right-sided fractured neck of femur requiring repair via a cemented hemiarthroplasty. Intraoperatively he received 10 mg of intravenous morphine. Post-operatively he received a short course of low-dose oral opioids and subsequently developed myoclonic jerks and hyperalgesia. The opioids were discontinued and both adverse effects resolved. This case report discusses the concurrent development of myoclonus and hyperalgesia following a low dose of opioids and explores possible management options.

Entities:  

Keywords:  Pain perception; adverse effect; hyperalgesia; myoclonus; opioid

Year:  2016        PMID: 28386402      PMCID: PMC5370622          DOI: 10.1177/2049463716664371

Source DB:  PubMed          Journal:  Br J Pain        ISSN: 2049-4637


  28 in total

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Authors:  N Hagen; R Swanson
Journal:  J Pain Symptom Manage       Date:  1997-07       Impact factor: 3.612

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Authors:  Larry F Chu; David J Clark; Martin S Angst
Journal:  J Pain       Date:  2006-01       Impact factor: 5.820

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Authors:  Seema Patel; Veda R Roshan; Kelly C Lee; Rebecca J Cheung
Journal:  Ann Pharmacother       Date:  2006-10-17       Impact factor: 3.154

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Authors:  Larry F Chu; Jutta Dairmont; Abigail K Zamora; Chelsea A Young; Martin S Angst
Journal:  J Pain       Date:  2011-01       Impact factor: 5.820

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Journal:  BMJ       Date:  1989-07-15

6.  Hyperalgesia and myoclonus in terminal cancer patients treated with continuous intravenous morphine.

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Journal:  Pain       Date:  1993-10       Impact factor: 6.961

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Authors:  Per Sjøgren; Niels-Henrik Jensen; Troels Staehelin Jensen
Journal:  Pain       Date:  1994-11       Impact factor: 6.961

Review 8.  Opioid-induced hyperalgesia in humans: molecular mechanisms and clinical considerations.

Authors:  Larry F Chu; Martin S Angst; David Clark
Journal:  Clin J Pain       Date:  2008 Jul-Aug       Impact factor: 3.442

9.  Myoclonic spasms following intrathecal diamorphine.

Authors:  P D Cartwright; C Hesse; A O Jackson
Journal:  J Pain Symptom Manage       Date:  1993-10       Impact factor: 3.612

10.  Comparison of the Effects of Low-Dose Midazolam, Magnesium Sulfate, Remifentanil and Low-Dose Etomidate on Prevention of Etomidate-Induced Myoclonus in Orthopedic Surgeries.

Authors:  Abbas Sedighinejad; Bahram Naderi Nabi; Mohammad Haghighi; Gelareh Biazar; Vali Imantalab; Siamak Rimaz; Zahra Zaridoost
Journal:  Anesth Pain Med       Date:  2016-04-02
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  5 in total

1.  A fall from grace: exposing the neurotoxicities of morphine.

Authors:  Sam H Ahmedzai
Journal:  Br J Pain       Date:  2016-10-13

2.  Endomorphin-2 Decreases Excitatory Synaptic Transmission in the Spinal Ventral Horn of the Rat.

Authors:  Zhen-Yu Wu; Ya-Cheng Lu; Ban Feng; Ying-Biao Chen; Yang Bai; Ting Zhang; Hua Zhang; Tao Chen; Yu-Ling Dong; Hui Li; Yun-Qing Li
Journal:  Front Neural Circuits       Date:  2017-08-08       Impact factor: 3.492

3.  Intrathecal morphine combined with ropivacaine induces spinal myoclonus in cancer patients with an implanted intrathecal drug delivery system: Three case reports.

Authors:  Xuejiao Guo; Yunze Li; Yixin Yang; Yimin Zhao; Jianguo Guo; Yanfeng Zhang; Zhiyou Peng; Zhiying Feng
Journal:  Medicine (Baltimore)       Date:  2019-05       Impact factor: 1.817

4.  Hyperkinetic reaction to dihydrocodeine.

Authors:  James David van Oppen; Neeta Patel; Aamir Tarique
Journal:  BMJ Case Rep       Date:  2020-01-21

5.  Management of orphan symptoms: ESMO Clinical Practice Guidelines for diagnosis and treatment.

Authors:  D Santini; G Armento; R Giusti; M Ferrara; C Moro; F Fulfaro; P Bossi; F Arena; C I Ripamonti
Journal:  ESMO Open       Date:  2020-11
  5 in total

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