Literature DB >> 28385778

Double autophagy stimulation using chemotherapy and mTOR inhibition combined with hydroxychloroquine for autophagy modulation in patients with relapsed or refractory multiple myeloma.

Emma C Scott1, Richard T Maziarz2, Stephen E Spurgeon2, Eva Medvedova2, James Gajewski2, Shara Reasor-Heard2, Byung Park3, Anne Kratz2, George V Thomas4, Marc Loriaux4, Michael Cascio4, Jennifer Podolak4, Miranda Gordon2, Jennifer Botelho2, Edward Stadtmauer5, Ravi Amaravadi5, Dan T Vogl5.   

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Year:  2017        PMID： 28385778      PMCID： PMC5566051          DOI： 10.3324/haematol.2016.162321

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  14 in total

1.  Targeting autophagy augments in vitro and in vivo antimyeloma activity of DNA-damaging chemotherapy.

Authors:  Yaozhu Pan; Ying Gao; Liang Chen; Guangxun Gao; Hongjuan Dong; Yang Yang; Baoxia Dong; Xiequn Chen
Journal:  Clin Cancer Res       Date:  2011-02-02       Impact factor: 12.531

2.  Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma.

Authors:  Dan T Vogl; Edward A Stadtmauer; Kay-See Tan; Daniel F Heitjan; Lisa E Davis; Laura Pontiggia; Reshma Rangwala; Shengfu Piao; Yunyoung C Chang; Emma C Scott; Thomas M Paul; Charles W Nichols; David L Porter; Janeen Kaplan; Gayle Mallon; James E Bradner; Ravi K Amaravadi
Journal:  Autophagy       Date:  2014-05-20       Impact factor: 16.016

Review 3.  Emerging strategies to effectively target autophagy in cancer.

Authors:  V W Rebecca; R K Amaravadi
Journal:  Oncogene       Date:  2015-04-20       Impact factor: 9.867

4.  A comparison of salvage infusional chemotherapy regimens for recurrent/refractory multiple myeloma.

Authors:  Patrick T Griffin; Viet Q Ho; William Fulp; Taiga Nishihori; Kenneth H Shain; Melissa Alsina; Rachid C Baz
Journal:  Cancer       Date:  2015-07-06       Impact factor: 6.860

Review 5.  Principles and current strategies for targeting autophagy for cancer treatment.

Authors:  Ravi K Amaravadi; Jennifer Lippincott-Schwartz; Xiao-Ming Yin; William A Weiss; Naoko Takebe; William Timmer; Robert S DiPaola; Michael T Lotze; Eileen White
Journal:  Clin Cancer Res       Date:  2011-02-15       Impact factor: 12.531

6.  Phase II trial of temsirolimus in patients with relapsed or refractory multiple myeloma.

Authors:  Sherif S Farag; Shuhong Zhang; Buffy S Jansak; Xiaojing Wang; Eric Kraut; Kenneth Chan; Janet E Dancey; Michael R Grever
Journal:  Leuk Res       Date:  2009-03-03       Impact factor: 3.156

7.  ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.

Authors:  Chang Hwa Jung; Chang Bong Jun; Seung-Hyun Ro; Young-Mi Kim; Neil Michael Otto; Jing Cao; Mondira Kundu; Do-Hyung Kim
Journal:  Mol Biol Cell       Date:  2009-02-18       Impact factor: 4.138

8.  Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation.

Authors:  Jing Lu; Tatiana Zavorotinskaya; Yumin Dai; Xiao-Hong Niu; Joseph Castillo; Janet Sim; Jianjun Yu; Yingyun Wang; John L Langowski; Jocelyn Holash; Kevin Shannon; Pablo D Garcia
Journal:  Blood       Date:  2013-07-01       Impact factor: 22.113

9.  Effect of autophagy on multiple myeloma cell viability.

Authors:  Bao Hoang; Angelica Benavides; Yijiang Shi; Patrick Frost; Alan Lichtenstein
Journal:  Mol Cancer Ther       Date:  2009-06-09       Impact factor: 6.261

10.  The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.

Authors:  Reuben J Shaw; Monica Kosmatka; Nabeel Bardeesy; Rebecca L Hurley; Lee A Witters; Ronald A DePinho; Lewis C Cantley
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-25       Impact factor: 11.205
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  7 in total

Review 1.  Targeting autophagy in cancer.

Authors:  Angelique V Onorati; Matheus Dyczynski; Rani Ojha; Ravi K Amaravadi
Journal:  Cancer       Date:  2018-04-19       Impact factor: 6.860

Review 2.  Targeting Autophagy in Cancer: Recent Advances and Future Directions.

Authors:  Ravi K Amaravadi; Alec C Kimmelman; Jayanta Debnath
Journal:  Cancer Discov       Date:  2019-08-21       Impact factor: 39.397

Review 3.  The pleiotropic functions of autophagy in metastasis.

Authors:  Timothy Marsh; Bhairavi Tolani; Jayanta Debnath
Journal:  J Cell Sci       Date:  2021-01-22       Impact factor: 5.285

4.  The Precision Control of Autophagic Flux and Vesicle Dynamics-A Micropattern Approach.

Authors:  André du Toit; Sholto De Wet; Jan-Hendrik S Hofmeyr; Kristian K Müller-Nedebock; Ben Loos
Journal:  Cells       Date:  2018-08-03       Impact factor: 6.600

Review 5.  The multifaceted role of autophagy in cancer and the microenvironment.

Authors:  Hendrik Folkerts; Susan Hilgendorf; Edo Vellenga; Edwin Bremer; Valerie R Wiersma
Journal:  Med Res Rev       Date:  2018-10-09       Impact factor: 12.944

Review 6.  Bisphosphonates for delivering drugs to bone.

Authors:  Shuting Sun; Jianguo Tao; Parish P Sedghizadeh; Philip Cherian; Adam F Junka; Esmat Sodagar; Lianping Xing; Robert K Boeckman; Venkatesan Srinivasan; Zhenqiang Yao; Brendan F Boyce; Brea Lipe; Jeffrey D Neighbors; R Graham G Russell; Charles E McKenna; Frank H Ebetino
Journal:  Br J Pharmacol       Date:  2021-04-10       Impact factor: 8.739

Review 7.  Autophagy and tumorigenesis.

Authors:  Michael Rangel; Jerry Kong; Vrushank Bhatt; Khoosheh Khayati; Jessie Yanxiang Guo
Journal:  FEBS J       Date:  2021-07-16       Impact factor: 5.542
  7 in total

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