Jiashen Shao1, Hengrui Chang2, Yanbin Zhu3, Wei Chen4, Zhanle Zheng5, Huixin Zhang6, Yingze Zhang7. 1. The Third Hospital of Hebei Medical University, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China; Key Laboratory of Biomechanics of Hebei Province, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China. Electronic address: shaojiashen@vip.qq.com. 2. The Third Hospital of Hebei Medical University, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China; Key Laboratory of Biomechanics of Hebei Province, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China. Electronic address: 18831178786@163.com. 3. The Third Hospital of Hebei Medical University, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China; Key Laboratory of Biomechanics of Hebei Province, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China. Electronic address: zhuyanbin111@126.com. 4. The Third Hospital of Hebei Medical University, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China; Key Laboratory of Biomechanics of Hebei Province, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China. Electronic address: drchenwei1981@gmail.com. 5. The Third Hospital of Hebei Medical University, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China; Key Laboratory of Biomechanics of Hebei Province, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China. Electronic address: lancelotzzl@qq.com. 6. The Third Hospital of Hebei Medical University, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China; Key Laboratory of Biomechanics of Hebei Province, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China. Electronic address: 1163953494@qq.com. 7. The Third Hospital of Hebei Medical University, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China; Key Laboratory of Biomechanics of Hebei Province, Orthopaedic Surgery, NO. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, People's Republic of China. Electronic address: drzhangyz@126.com.
Abstract
BACKGROUND: This study aimed to quantitatively summarize the risk factors associated with surgical site infection after open reduction and internal fixation of tibial plateau fracture. METHODS: Medline, Embase, CNKI, Wanfang database and Cochrane central database were searched for relevant original studies from database inception to October 2016. Eligible studies had to meet quality assessment criteria according to the Newcastle-Ottawa Scale, and had to evaluate the risk factors for surgical site infection after open reduction and internal fixation of tibial plateau fracture. Stata 11.0 software was used for this meta-analysis. RESULTS: Eight studies involving 2214 cases of tibial plateau fracture treated by open reduction and internal fixation and 219 cases of surgical site infection were included in this meta-analysis. The following parameters were identified as significant risk factors for surgical site infection after open reduction and internal fixation of tibial plateau fracture (p < 0.05): open fracture (OR 3.78; 95% CI 2.71-5.27), compartment syndrome (OR 3.53; 95% CI 2.13-5.86), operative time (OR 2.15; 95% CI 1.53-3.02), tobacco use (OR 2.13; 95% CI 1.13-3.99), and external fixation (OR 2.07; 95% CI 1.05-4.09). Other factors, including male sex, were not identified as risk factors for surgical site infection. CONCLUSION: Patients with the abovementioned medical conditions are at risk of surgical site infection after open reduction and internal fixation of tibial plateau fracture. Surgeons should be cognizant of these risks and give relevant preoperative advice.
BACKGROUND: This study aimed to quantitatively summarize the risk factors associated with surgical site infection after open reduction and internal fixation of tibial plateau fracture. METHODS: Medline, Embase, CNKI, Wanfang database and Cochrane central database were searched for relevant original studies from database inception to October 2016. Eligible studies had to meet quality assessment criteria according to the Newcastle-Ottawa Scale, and had to evaluate the risk factors for surgical site infection after open reduction and internal fixation of tibial plateau fracture. Stata 11.0 software was used for this meta-analysis. RESULTS: Eight studies involving 2214 cases of tibial plateau fracture treated by open reduction and internal fixation and 219 cases of surgical site infection were included in this meta-analysis. The following parameters were identified as significant risk factors for surgical site infection after open reduction and internal fixation of tibial plateau fracture (p < 0.05): open fracture (OR 3.78; 95% CI 2.71-5.27), compartment syndrome (OR 3.53; 95% CI 2.13-5.86), operative time (OR 2.15; 95% CI 1.53-3.02), tobacco use (OR 2.13; 95% CI 1.13-3.99), and external fixation (OR 2.07; 95% CI 1.05-4.09). Other factors, including male sex, were not identified as risk factors for surgical site infection. CONCLUSION:Patients with the abovementioned medical conditions are at risk of surgical site infection after open reduction and internal fixation of tibial plateau fracture. Surgeons should be cognizant of these risks and give relevant preoperative advice.
Authors: Alan G Shamrock; Zain Khazi; Trevor R Gulbrandsen; Kyle R Duchman; Michael C Willey; Matthew D Karam; Matthew H Hogue; J Lawrence Marsh Journal: Arthrosc Sports Med Rehabil Date: 2020-09-12